Sökning: "binding specificities"
Visar resultat 16 - 20 av 62 avhandlingar innehållade orden binding specificities.
16. Genetic re-targeting of adenoviral vectors for gene therapy applications
Sammanfattning : The adenovirus (Ad) is a frequent cause of upper respiratory tract infections, enteritis and conjunctivitis. Since its first isolation in 1953, the study of Ad has contributed greatly to the understanding of intracellular events and has also served as a model system for many viruses. LÄS MER
17. Combinatorial protein engineering applied to enzyme catalysis and molecular recognition
Sammanfattning : The recent development of methods for constructing andhandling large collections (libraries) of proteins, from whichvariants with desired traits can be isolated, hasrevolutionized the field of protein engineering. Key elementsof such methods are the various ways in which the genotypes(the genes) and the phenotypes (the encoded proteins) arephysically linked during the process. LÄS MER
18. Generation and engineering of ABD-derived affinity proteins for clinical applications
Sammanfattning : Proteins that specifically recognize and bind to other molecules or structures are important tools in industrial and medical applications. Binding proteins engineered from small stable scaffold proteins have been utilized for several purposes due to their favorable biophysical properties, tolerance to mutagenesis, efficient tissue penetration and ease of production. LÄS MER
19. Human salivary esterases : a biochemical study of carboxylesterase and thio-esterase in human saliva with special reference to their inhibition by dental materials
Sammanfattning : Electrophoretic and gel chromatographic techniques have been developed in order to obtain partially purified esterases from small amounts of human saliva. These techniques permit the characterization of salivary esterase regarding substrate and inhibitor specificities, and lectin binding ability. LÄS MER
20. Adhesion-related interactions of Actinomyces and Streptococcus biofilm bacteria
Sammanfattning : Adhesion of bacteria is a key event in biofilm formation and is mediated by bacterial adhesins recognising host or bacterial partner receptors. In oral biofilm formation, primary Actinomyces and Streptococcus colonizers adhere to salivary pellicle proteins such as proline-rich proteins (PRPs) as well as to mucosal surfaces. LÄS MER