Sökning: "aryl halides"

Visar resultat 16 - 19 av 19 avhandlingar innehållade orden aryl halides.

  1. 16. Methods for the Synthesis of PET Tracers and NMR Studies of Ribonuclease A

    Författare :Linda Samuelsson; Bengt Långström; Sharon Stone-Elander; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; [11C]methyl iodide; Stille reaction; palladium; Ribonuclease A; osmolytes; PFG-NMR; Organisk kemi; Organic chemistry; Organisk kemi;

    Sammanfattning : This thesis contains two parts.In the first part, general and versatile palladium-mediated 11C-C bond forming reactions for use in the production of radiotracers for Positron Emission Tomography (PET) were explored. LÄS MER

  3. 17. Palladium(0)-Catalysed Carbonylative Multicomponent Reactions : Synthesis of Heterocycles and the Application of Quinolinyl Pyrimidines as Enzyme Inhibitors

    Författare :Linda Åkerbladh; Mats Larhed; Luke Odell; Anders Karlén; Lise-Lotte Gundersen; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Palladium catalysis; Carbonylation; Multicomponent reactions; Domino reactions; Heterocycles; 4-Quinolones; 2-Aminoquinazolinones; Benzoxazinones; N-Acylguanidines; Type II NADH dehydrogenase; NDH-2;

    Sammanfattning : Palladium-catalysed carbonylative multicomponent reactions have proven useful for the synthesis of structurally diverse compounds. Carbon monoxide serves as an atom-efficient, one-carbon building block, which allows for further structural elaboration of the carbonyl compound. LÄS MER

  4. 18. Method development for [11C]carbon monoxide radiochemistry

    Författare :Mélodie Ferrat; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Positron emission tomography (PET) is a non-invasive molecular imaging technique that has found extensive utility in biomedical research and in drug development. A fundamental pre-requisite for PET is the tracer, which is a biologically relevant molecule, labeled with a short-lived radionuclide. LÄS MER

  5. 19. Metallacyclic Phosphine Complexes and Intramolecular Csp3-H Bond Activation -Synthesis, Characterisation and Catalytic Application

    Författare :Sven Sjövall; Kemiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; catalysis; Heck; diphosphite; diphosphine; phosphine; cyclometallation; C-C activation; C-O activation; C-H activation; palladium; rhodium; iridium; Inorganic chemistry; Oorganisk kemi;

    Sammanfattning : The work presented in this thesis deals with metallacyclic late transition metal complexes, obtained by intramolecular Csp3-H activation, and the application of such compounds in catalysis. The new hemilabile P,O phosphines N-methyl-N-propionyl-2-(diphenylphosphino)benzylamine (DPPAM), o-(diphenylphosphino)benzoic acid ethyl ester (DPPES), o-(diphenylphosphino)benzoic acid methyl ether (DPPET) and ±-1-(2- diphenylphosphino)phenylethyl propionate (±-DPPMES) and the symmetrical diphosphorus donor ligands cis-1,3-bis[(diphenylphosphino)methyl]-cyclohexane (DPCY), cis-1,3-bis[(di-tertbutylphosphino)methyl]cyclohexane (DTBCY) and cis-1,3-bis[(di-isopropylphosphino)methyl]cyclohexane (DIPCY) have been synthesised, allowing the preparation of a range of new metallacyclic rhodium(III), iridium(III) and palladium(II) complexes. LÄS MER