Sökning: "allogeneic hematopoietic stem cell transplantation"

Visar resultat 1 - 5 av 56 avhandlingar innehållade orden allogeneic hematopoietic stem cell transplantation.

1. 1. Life situation in patients and their family members after allogeneic hematopoietic stem cell transplantation : aspects of health and support in different care settings

   Författare :Karin Bergkvist; Joacim Larsen; Jonas Mattsson; Unn-Britt Johansson; Karin Ahlberg; Sophiahemmet Högskola; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Allogeneic hematopoietic stem cell transplantation; Family member; Home care; Hospital care; Patient reported experiences; Patient reported outcomes; allogeneic hematopoietic stem cell transplantation;

   Sammanfattning : Allogeneic hematopoietic stem cell transplantation (HSCT) is mainly an intensive treatment option for hematology malignancies. During the past decades, improved care and treatment have been systematically developed. LÄS MER

3. 2. Immune reconstitution after allogeneic hematopoietic stem cell transplantation

   Författare :Brigitta Omazic; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Immune reconstitution; allogeneic haematopoietic stem cell transplantation; IgH gene expression; TcRVbeta gene expression; B lymphocytes; T lymphocytes; IGF-1 receptor; thyroid hormone receptor.;

   Sammanfattning : After treatment with allogeneic hernatopoietic stem cell transplantation (HSCT) the patient suffers from a deficient immune system for at least 12 months or longer. During this period, the patient is susceptible to infections and if the state of immune deficiency is prolonged there is an increased risk of relapse of the underlying malignancy as well as development of secondary malignancies. LÄS MER

4. 3. Pulmonary complications after allogeneic hematopoietic stem cell transplantation

   Författare :Ulrica Forslöw; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The respiratory tract is one of the most common and serious sites for complications in HSCT patients. In this project the incidence, outcome, and risk factors for patients with infectious or non-infectious pulmonary complications were studied. Bronchoscopy and pulmonary function tests (PFTs) were evaluated as diagnostic tools. LÄS MER

5. 4. Alloreactivity in stem cell transplantation

   Författare :Anna Nordlander; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Acute graft-versus-host disease (GVHD), relapse and graft rejection are the main complications after allogeneic hematopoietic stem cell transplantation (HSCT). The aim of this thesis was to achieve a better understanding of the alloreactivity seen after HSCT, focusing on graft rejection, but also including the graft-versus-leukemia (GVL) effect and GVHD. LÄS MER

7. 5. Myofibroblasts and polyploid cells in the conjunctival surface after allogeneic hematopoietic stem cell transplantation

   Författare :David Hallberg; Göteborgs universitet; []
   Nyckelord :Myofibroblast; Polyploid; Allogeneic; Graft-versus-Host Disease;

   Sammanfattning : Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a potentially curative treatment modality for hematological malignancies, such as leukemia and lymphoma. However, a major complication of the procedure is that the immune effector cells in the graft may become activated towards the host´s healthy tissues, resulting in a condition called Graft-versus-Host Disease (GvHD). LÄS MER