Sökning: "airway epithelium"

Visar resultat 31 - 35 av 62 avhandlingar innehållade orden airway epithelium.

  1. 31. Respiratory effects of particulate matter air pollution : studies on diesel exhaust, road tunnel, subway and wood smoke exposure in human subjects

    Författare :Maria Sehlstedt; Sandström Thomas; Jamshid Pourazar; Anders Bucht; Steffen Loft; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Airway inflammation; antioxidant; bronchoscopy; detoxification; immunohistochemistry; particulate matter; Environmental medicine; Miljömedicin;

    Sammanfattning : Background: Ambient air pollution is associated with adverse health effects, but the sources and components, which cause these effects is still incompletely understood. The aim of this thesis was to investigate the pulmonary effects of a variety of common air pollutants, including diesel exhaust, biomass smoke, and road tunnel and subway station environments. LÄS MER

  3. 32. Analysis of Endogenous Particles in Exhaled Air

    Författare :Ann-Charlotte Almstrand; Göteborgs universitet; []
    Nyckelord :exhaled particles; time-of-flight secondary ion mass spectrometry; OPLS; airway closure; exhaled breath condensate; glutathione;

    Sammanfattning : Exhaled air contains non-volatile particulate material from the respiratory tract. The precise location in which exhaled particles are formed is unknown, and details on their chemical content are scarce. The aim of this work was to chemically characterize and to study the mechanisms of formation of endogenous particles in exhaled air. LÄS MER

  4. 33. Haemophilus influenzae adhesins and the innate immune response

    Författare :Elena Ronander; Malmö Klinisk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; inflammation; Haemophilus influenzae; Haemophilus surface fibrils; complement; innate immune response; protein E; respiratory epithelium; adhesins;

    Sammanfattning : Haemophilus influenzae is a human specific Gram-negative respiratory tract pathogen. Encapsulated H. influenzae strains exist in six different serotypes a-f, of which type b (Hib) is the most virulent. Hib is protected by the polysaccharide capsule when invading the blood circulaton and may cause diseases such as meningitis and epiglottitis. LÄS MER

  5. 34. Prostaglandin E2 as mediator and modulator of airway smooth muscle responses

    Författare :Jesper Säfholm; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Prostaglandin E2 (PGE2) is a lipid mediator produced by virtually every cell of the human body. Because common non-steroidal anti-inflammatory drugs (NSAIDs) inhibit its biosynthesis, PGE2 is usually considered to be a ‘pro-inflammatory’ mediator. The role of PGE2 in the lung and airways has however always been unclear. LÄS MER

  7. 35. Sensory mechanisms in the human upper airway - Role of TRP ion channels

    Författare :Lisa Alenmyr; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TRPV1; TRPV4; TRPA1; allergic rhinitis; itch; rhinorrhea; MUC5B; MUC5AC; epithelial;

    Sammanfattning : The nasal mucosa is richly innervated with sensory nerves having the ability to detect changes in the environment and mediate symptoms such as secretion and itch. Some TRP ion channels such as TRPV1 and TRPA1 are abundantly expressed in sensory nerves and respond to a wide variety of stimuli, including irritants, inflammatory mediators and temperatures. LÄS MER