Sökning: "epithelial"

Visar resultat 1 - 5 av 1038 avhandlingar innehållade ordet epithelial.

  1. 1. New Approaches to Studies of Paracellular Drug Transport in Intestinal Epithelial Cell Monolayers

    Författare :Staffan Tavelin; Per Artursson; Staffan Tavelin; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; intestinal epithelium; tight junctions; cell culture; Galenisk farmaci; Pharmaceutics; Galenisk farmaci; galenisk farmaci; Pharmaceutics;

    Sammanfattning : Studies of intestinal drug permeability have traditionally been performed in the colon-derived Caco-2 cell model. However, the permeability of these cell monolayers resembles that of the colon rather than that of the small intestine, which is the major site of drug absorption following oral administration. LÄS MER

  2. 2. Airway epithelial shedding: Morphological and functional aspects in vivo

    Författare :Jonas Erjefält; Luftvägsinflammation; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; eosinophils; neutrophils; plasma exudation; barrier restitution; basal cells; ciliated cells; secretory cells; Epithelial repair; epithelial shedding; fibrinogen; fibronectin; Respiratory system; Andningsorganen;

    Sammanfattning : Epithelial damage may contribute to the pathology in airway diseases such as asthma and rhinitis. However, the distribution of epithelial shedding in inflammatory airway diseases and, particularly, the ensuing repair processes are largely unknown. LÄS MER

  3. 3. Molecular regulation of epithelial tube size

    Författare :Erika Tång Hallbäck; Göteborgs universitet; []
    Nyckelord :Drosophila; tube shape; trachea; chitin; luminal matrix; epithelial tubes; morphogenesis; chloride channel; subapical actin;

    Sammanfattning : In nature, epithelial tubes are vital structures in organ design and are required for transport of gases and liquids in organs, such as the vascular system, the vertebrate lung and the kidneys. The tubular epithelium is single layered, but is often reinforced by layers of muscular support. LÄS MER

  4. 4. p63 and epithelial homeostasis : studies of p63 under normal, hyper-proliferative and malignant conditions

    Författare :Xiaolian Gu; Karin Nylander; Antonio Costanzo; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; p63; psoriasis; SCCHN; epithelium; homeostasis; Pathology; Patologi; patologi; Pathology;

    Sammanfattning : Background: The p63 gene is a member of the p53 transcription factor family and can produce six different proteins using two promoters and differential splicing. Expression of p63 is required for proper formation of epithelial tissues. LÄS MER

  5. 5. Cell Contacts and Airway Epithelial Damage in Asthma

    Författare :Shahida Shahana; Godfried Roomans; Rolf Odselius; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anatomy; Desmosomes; tight junctions; major basic protein; eosinophil; cytokines; epithelial damage.; Anatomi; Anatomy; Anatomi;

    Sammanfattning : Airway epithelial damage is commonly found in asthma patients. Epithelial damage was investigated with special reference to contacts between epithelial cells.Eosinophils, common in allergic asthma, secrete cationic proteins, particularly major basic protein (MBP). LÄS MER