Sökning: "adult neural stem cells"

Visar resultat 11 - 15 av 104 avhandlingar innehållade orden adult neural stem cells.

1. 11. Integration and function of new neurons generated from fibroblasts and adult neural stem cells in the pathological brain

   Författare :James Wood; Lund Neurologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurogenesis; neural stem cells; iNs; iPS cells; stroke; epilepsy; electrophysiology;

   Sammanfattning : In Papers One through Six we have investigated the function and integration of “new” neurons – new neurons born from neural stem cells in the adult brain, and new neurons in the sense that they were generated from fibroblasts. Papers One and Two focused on the new neurons generated from neural stem cells in the SVZ and SGZ after pathological insults. LÄS MER

3. 12. Stem cells : proliferation, differentiation, migration

   Författare :Anna Falk; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Embryonic stem cell; adult neural stem cells; proliferation; differentiation; migration;

   Sammanfattning : A stem cell is demanding and requires precise conditions to carry out its unique tasks. This includes proliferation as an undifferentiated stem cell, differentiation to more mature cell types, migration through tissue to its final destination, and functional integration into the cellular network. LÄS MER

4. 13. Dental mesenchymal stem cells

   Författare :Nina Kaukua; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Mesenchymal stem cells have been found in various tissues and act as source for renewal and repair. The mouse incisor tooth continuously grows throughout life, implicating that there are stem cell niches constantly contributing with cells. The composition of these stem cell niches is not fully understood. LÄS MER

5. 14. Molecular specification of expanded forebrain neural stem and progenitor cells

   Författare :Malin Parmar; Neurobiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; teratology; ontogeny; embryology human ; Development biology; developmental control genes; in vitro expansion; transplantation; precursor cell; stem cells; progenitor cell; human; mouse; Utvecklingsbiologi; teratologi; embryologi människa ;

   Sammanfattning : The molecular specification of neural precursor cells has been suggested to be a progressive process, with a transition from an early requirement for extrinsic signals to intrinsic mechanisms. Thus, the cells in the nervous system acquire distinct fates in response to extrinsic signals, which activate repertoires of transcription factors in a region and cell type specific manner. LÄS MER

7. 15. Regional differences in the response of neural stem cells and their microenvironment to ionizing radiation

   Författare :Nina Hellström; Göteborgs universitet; []
   Nyckelord :ionizing radiation; neurogenesis; neural stem cells; inflammation; microglia; stem cell niche; trophic support;

   Sammanfattning : Radiation therapy is one of the most effective tools for treating malignant tumors; however, cranial irradiation often results in intellectual impairment and cognitive deficits, such as impaired learning and memory. Ionizing radiation generates DNA damage, causing proliferative cells to undergo apoptosis. LÄS MER