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Visar resultat 1 - 5 av 12 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. The role of the Type IV pili system in the virulence of Francisella tularensis

    Författare :Emelie Salomonsson; Åke Forsberg; Jean-Pierre Gorvel; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Francisella tularensis; tularemia; bacterial pathogenesis; Type IV pili; Type II secretion; Neisseria gonorrhoeae; PilA; RD18; RD19; Molecular biology; Molekylärbiologi;

    Sammanfattning : Francisella tularensis is a Gram-negative intracellular pathogen causing the zoonotic disease tularemia. F. tularensis can be found almost all over the world and has been recovered from several animal species, even though the natural reservoir of the bacterium and parts of its life cycle are still unknown. LÄS MER

  2. 2. Type III Secretion Mediated Translocation of Effector Exoenzymes by Pseudomonas aeruginosa

    Författare :Charlotta Sundin; Åke Forsberg; Anthony Pugsley; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Pseudomonas aeruginosa; type III secretion system; ExoS; ExoT; PcrV; PcrG; PopB; PopD; PopN; type IV pili; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : .... LÄS MER

  3. 3. Lifestyle and Genome Evolution in Vector-Borne Bacteria : A Comparison of Three Bartonella Species

    Författare :Anna Carolin Frank; Siv Andersson; Stewart Cole; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology; Bartonella; evolution; host-restriction; vector-borne; horizontal gene transfer; genome reduction; alpha-proteobacteria; Type-IV secretion; Biologi; Biology; Biologi;

    Sammanfattning : Bacterial genomes provide records of the molecular processes associated with emergence and evolution of different bacterial lifestyles. This thesis is based on whole-genome comparisons within the genus Bartonella, an excellent model system for studies of host- and vector-specificity and infection outcome in animal-associated bacteria. LÄS MER

  4. 4. Basement membrane components in the chondrocyte extracellular matrix

    Författare :Alexander Kvist; Lunds universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Skelett; rheumatology locomotion; nidogen; chondroitin sulfate; collagen assembly; Skeleton; muscle system; type IV collagen; laminin; perlecan; basement membranes; ECM; chondrcytes; muskelsystem; reumatologi;

    Sammanfattning : The extracellular matrix (ECM) is a network of macromolecules which, together with cells, forms the various tissues of all metazoan organisms. Cartilage, in contrast to most other tissues, contains relatively few cells in proportion to the volume occupied by ECM. LÄS MER

  5. 5. Identification of new virulence factors in Francisella tularensis

    Författare :Anna-Lena Forslund; Åke Forsberg; Elisabeth Carniel; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Francisella tularensis; regulation; virulence; Hfq; DsbA; type IV pili; membrane; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : Francisella tularensis, the causative agent of tularemia, is a highly virulent bacterium with an infection dose of less than ten bacteria. The ability of a pathogen to cause infection relies on different virulence mechanisms, but in Francisella tularensis relatively few virulence factors are known. Two F. LÄS MER