Sökning: "collagen assembly"
Visar resultat 1 - 5 av 21 avhandlingar innehållade orden collagen assembly.
1. Collagen VI - Molecular Assembly and Interactions
Sammanfattning : The extracellular matrix plays an integral role in tissue remodeling and development and it defines the different mechanical properties of a variety of connective tissues. Its complexity in composition and the details in organization has only been partly elucidated. LÄS MER
2. The role of leucine-rich repeat glycoproteins/proteoglycans in the assembly of collagen matrices
Sammanfattning : The properties of different connective tissues depend on the synthesis and assembly of macromolecular structures composed of collagen and other extracellular matrix components. Mechanisms modulating these events play important roles in the formation of a functional tissue. LÄS MER
3. Basement membrane components in the chondrocyte extracellular matrix
Sammanfattning : The extracellular matrix (ECM) is a network of macromolecules which, together with cells, forms the various tissues of all metazoan organisms. Cartilage, in contrast to most other tissues, contains relatively few cells in proportion to the volume occupied by ECM. LÄS MER
4. Proteoglycan Lectin Domain Interactions in Extracellular Matrix Assembly
Sammanfattning : This thesis focuses on the C-terminal G3 region of the large aggregating proteoglycans that are found in complex with hyaluronan in the extracellular matrix. The G3 region contains a C-type lectin domain that binds different extracellular matrix proteins playing an integral role in tissue organization during development and remodeling. LÄS MER
5. Fibromodulin and chondroadherin in connective tissue homeostasis
Sammanfattning : Connective tissue contains a prominent extracellular matrix (ECM), which provides for physiological and mechanical properties. Intra- and inter-molecular interactions between proteins in this ECM provide for the formation of molecular networks. These interactions determine the shape of the tissue as well as cell behavior. LÄS MER