Sökning: "Tumor stroma"

Visar resultat 16 - 20 av 77 avhandlingar innehållade orden Tumor stroma.

  1. 16. TINT Tumor Indicating Normal Tissue : new field of diagnostic biomarkers for prostate cancer

    Författare :Hanibal Hani Adamo; Anders Bergh; Göran Landberg; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostate cancer; biomarkers; TINT; patologi; Pathology;

    Sammanfattning : Background: Prostate cancer is the most common cancer in Sweden. Due its highly variable behavior, multifocal nature, and insufficient diagnostic methods, prostate cancer is difficult to diagnose and prognosticate. LÄS MER

  3. 17. Regulation of cellular growth and identification of stromal gene signatures in breast cancer

    Författare :Sofia Winslow; Avdelningen för translationell cancerforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; cellular stress; proliferation; PKCα; G3BP; PMP22; miR-34c; gene expression profiles; stroma;

    Sammanfattning : Normal tissue is tightly controlled to keep a balance between reproduction and elimination of cells. In cancer, these regulated processes are disrupted, resulting in uncontrolled cell growth. Regulation of RNA stability and turnover is important to maintain cellular homeostasis and can be controlled by various mechanisms. LÄS MER

  4. 18. Distal cholangiocarcinoma - from novel biomarkers to clinical management and outcome

    Författare :Johannes Byrling; Lund Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Distal cholangiocarcinoma; biliary tract cancer; periampullary cancer; pancreatoduodenectomy; lymph node metastasis; stroma; SPARC; THBS2; biomarker; mass spectrometry; Diagnosis; histopathology;

    Sammanfattning : Cholangiocarcinoma is an aggressive malignacy arising from the biliary tree. Anatomical subtypes ofcholangiocarcinoma differs in tumor biology and clinical management. Distal cholangiocarcinoma (dCCA)originates from the common bile duct. LÄS MER

  5. 19. Interactions between Malignant Keratinocytes and Fibroblasts : Studies in Head and Neck Squamous Cell Carcinoma

    Författare :Malin Hakelius; Daniel Nowinski; Bengt Gerdin; Kristofer Rubin; Avni Abdiu; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; coculture; extracellular matrix; interleukin-1 alpha; tumor stroma; differential gene regulation; innate response; Plastic Surgery; Plastikkirurgi;

    Sammanfattning : Carcinoma growth requires a supportive tumor stroma. The concept of reciprocal interactions between tumor and stromal cells has become widely acknowledged and the connective tissue activation seen in the malignant process has been likened to that of a healing wound. LÄS MER

  7. 20. Impact of pregnancies on ovarian cancer : Risk, prognosis and tumor biology

    Författare :Camilla Sköld; Ingrid Glimelius; Karin Stålberg; Anthoula Koliadi; Gunilla Enblad; Annika Idahl; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epithelial ovarian cancer; non-epithelial ovarian cancer; reproductive history; parity; risk factor; survival; progesterone receptor;

    Sammanfattning : Ovarian cancer is the most lethal gynecological malignancy. The etiology is complex and not fully understood, partly since ovarian cancer is not one distinct disease, but rather several histologically and clinically different subtypes. LÄS MER