Sökning: "differential gene regulation"
Visar resultat 1 - 5 av 109 avhandlingar innehållade orden differential gene regulation.
Sammanfattning : .... LÄS MER
Sammanfattning : Neuroblastoma patients show remarkable clinical heterogeneity, with courses ranging from spontaneous regression to fatal tumor progression despite intense multi-modal treatment. Previous studies have shown that hypoxia pushes neuroblastoma cells towards a more immature phenotype, which correlates to aggressive disease. LÄS MER
Sammanfattning : It is important to understand the processes of carcinogenesis and to find out which genes are involved . One way to study the process on a molecular basis is to identify differences in gene expression. LÄS MER
Sammanfattning : In this thesis, the biochemical mechanisms for complement activation by endogenous proteins are explored. The short leucine-rich repeat proteins (SLRPs) help organise extracellular matrices. We found that several SLRPs bind C1q and of these, fibromodulin and osteoadherin trigger complement. LÄS MER
Sammanfattning : Gene regulation implicates an important role in organismal complexity through contributing to phenotypic variation. In my thesis, I studied three diverse components of gene regulatory networks including transcription factors, DNA methylation and microRNAs to elucidate their role in vertebrates. LÄS MER