Sökning: "T-cell lymphoma"

Visar resultat 6 - 10 av 61 avhandlingar innehållade orden T-cell lymphoma.

1. 6. Improvement of adoptive T-cell therapy for Cancer

   Författare :Chuan Jin; Magnus Essand; Ola Winqvist; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CAR T-cell therapy; AEP expansion protocol; scaffold matrix attachment region; non-integrating lentivirus; H. pylori Neutrophil-activating protein; allogeneic DCs; Klinisk immunologi; Clinical Immunology;

   Sammanfattning : Cancer immunotherapy has recently made remarkable clinical progress. Adoptive transfer of T-cells engineered with a chimeric antigen receptor (CAR) against CD19 has been successful in treatment of B-cell leukemia. LÄS MER

3. 7. Genetic Alterations in Lymphoma : with Focus on the Ikaros, NOTCH1 and BCL11B Genes

   Författare :Anneli Karlsson; Peter Söderkvist; Shi-Mei Zhuang; Jan-Ingvar Jönsson; Dan Grandér; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell proliferation; Lymphoma; Znfn1a1; Notch1; Bcl11b; chromosomal regions; Ikaros; B-cell lymphomas; Oncology; Onkologi;

   Sammanfattning : Cell proliferation is a process that is strictly regulated by a large number of proteins. An alteration in one of the encoding genes inserts an error into the regulative protein, which may result in uncontrolled cell growth and eventually tumor formation. LÄS MER

4. 8. T cell dependent B lymphocyte activation, growth and maturation : the role of lymphokines

   Författare :Sven Pettersson; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TH cell activated B- cell growth maturation B-cell growth factor BSF-pI B-cel1 maturation factor s BMA neonatal B-cell prol iferation anti body secretion;

   Sammanfattning : The present work concerns the regulation of B cell activation, growth and terminal differentiation of helper T cells.T cell dependent (TD) B cell activation requires physical cell to cell contact between competent helper T cells (TH) and B cells and the recognition of MHC Class II antigens. LÄS MER

5. 9. Potential New Drugs in Lymphoma

   Författare :Maryam Delforoush; Gunilla Enblad; Mattias Berglund; Christina Drott; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lymphoma; diffuse large B-cell lymphoma; DLBCL; picropodophyllin; PPP; J1; melflufen; prodrug; cancer therapeutics; alkylating agents; b-AP15; proteasome inhibitors; DUB inhibition; UCHL5; USP14;

   Sammanfattning : Lymphomas are malignant tumours arising from cells in the lymphatic system. They are classified as B-cell lymphomas, T-cell lymphomas and Hodgkin lymphoma (HL). Of the B-cell lymphomas, one of the most common is diffuse large B-cell lymphoma (DLBCL). LÄS MER

7. 10. Cancer imaging and image analysis methods in whole-body MRI and PET/MRI

   Författare :Therese Sjöholm; Joel Kullberg; Filip Malmberg; Robin Strand; Håkan Ahlström; Einar Heiberg Brandt; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; magnetic resonance imaging; diffusion weighted imaging; positron emission tomography; whole-body imaging; normal atlas; CAR T-cell therapy; lymphoma; medical image analysis; Computerized Image Processing; Datoriserad bildbehandling;

   Sammanfattning : Diagnostic medical imaging techniques such as magnetic resonance imaging (MRI) and positron emission tomography (PET) can provide structural and functional assessments of the whole body. This has great value for potentially systemic diseases such as cancer. LÄS MER