Sökning: "Standard cell"
Visar resultat 11 - 15 av 519 avhandlingar innehållade orden Standard cell.
11. Cell and gene therapy for blood disorders. Modeling of novel treatment strategies for Gaucher type 1 disease and Diamond-Blackfan anemia in mice
Sammanfattning : Gaucher disease type 1 (GD type 1) and Diamond-Blackfan anemia (DBA) are rare genetic disorders affecting the hematopoietic system and routinely treated by administration of drugs with variable clinical efficacy. Though effective in alleviating disease symptoms in large cohorts of patients, these treatment options have the major drawback of being non-curative. LÄS MER
12. Ribosomal proteins L5, L15 and elongation factor 2, three vital components of the translation machinery : Functional features of RPL5, RPL15 and EF2 from Saccharomyces cerevisiae studied in vivo
Sammanfattning : Protein synthesis is an essential, energy consuming and tightly regulated process in all living cells. A central core of the cellular protein-factory is a macromolecule called ribosome. Ribosomes are composed of ribosomal RNAs (rRNAs) and proteins (RPs). Additional components such as elongation factors (EFs) also contribute to this process. LÄS MER
13. Nanowires in Cell Biology
Sammanfattning : This thesis explores the interactions between cells and nanowires, to increase our understanding of how cells are affected and how they can be manipulated by these one-dimensional, semiconductor crystals (lengths 1-10 µm, diameters .... LÄS MER
14. Functionalization and characterization of surface supported lipid membranes and their application in cell culture
Sammanfattning : Phospholipid bilayers supported on a solid surface constitute a versatile, biomimetic platform for a variety of applications, such as biosensing, drug delivery research, cell engineering and as cell membrane mimics in fundamental cell research. Phosphocholine supported lipid bilayers are resistant to cell attachment in a wide range of conditions, and can be functionalized with bioactive signaling molecules to promote specific interactions with cells. LÄS MER
15. Non-Standard Crystallography : Examples in 3- and 3+1 Dimensional Space
Sammanfattning : Crystallography today is by many seen as merely a tool for determining the structure of a material on the atomic level. It is expected that whatever comes out of the tool is the indisputable truth, a fact. This thesis is based on five publications illustrating that this is very far from the real world of materials research. LÄS MER