Sökning: "Scavenger receptor"

Visar resultat 11 - 15 av 48 avhandlingar innehållade orden Scavenger receptor.

1. 11. Cell-penetrating peptides; chemical modification, mechanism of uptake and formulation development

   Författare :Kariem Ezzat; Ülo Langel; Steven Dowdy; Stockholms universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cell penetrating peptides; gene therapy; scavenger receptors; pharmaceutical formulation; solid dispersion; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

   Sammanfattning : Gene therapy holds the promise of revolutionizing the way we treat diseases. By using recombinant DNA and oligonucleotides (ONs), gene functions can be restored, altered or silenced according to the therapeutic need. LÄS MER

3. 12. Cell-penetrating peptides and oligonucleotides : Design, uptake and therapeutic applications

   Författare :Andrés Muñoz-Alarcón; Ülo Langel; Sandrine Sagan; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell-penetrating peptides; oligonucleotides; scavenger receptors; telomerase; gene therapy; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

   Sammanfattning : Regulation of biological processes through the use of genetic elements is a central part of biological research and also holds great promise for future therapeutic applications. Oligonucleotides comprise a class of versatile biomolecules capable of modulating gene regulation. LÄS MER

4. 13. Towards a detailed understanding of the red blood cell storage lesion : and its consequences for in vivo survival following transfusion

   Författare :Andreas Hult; Christer Malm; Per-Arne Oldenborg; Martin L. Olsson; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Red blood cell; erythrocyte; transfusion; macrophage; phagocytosis; storage lesion; eryptosis; Class A scavenger receptor; transfusion medicine; transfusionsmedicin;

   Sammanfattning : Red blood cells (RBCs) are vital for oxygen delivery to tissues and constitute the vast majority of all cells in blood. After leaving the red bone marrow as mature cells, RBCs have a lifespan of approximately 120 days before they are removed from the circulation by macrophages, mainly in the spleen and liver. LÄS MER

5. 14. Structural and functional studies of class A scavenger receptors MARCO (SCARA2) and SCARA5

   Författare :Juha Ojala; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Our bodies are constantly exposed to various microorganisms and there is a constant battle between their survival and ours. Fortunately we are equipped with our immune system that takes remarkably good care of us, but when it fails we all know the consequences. LÄS MER

7. 15. The influence of quartz and surfactant on immune responses

   Författare :Göran Zetterberg; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :alveolar macrophages; complement receptor 1 and 3; interstitial macrophages; Iysophosphatidylcholine; phospholipids; quartz; rats; receptor expression; surfactant.;

   Sammanfattning : Pulmonary surfactant is a mixture of lipids and proteins that embeds the alveolar cells, has surface tension reducing properties but also influences the immune response. To further investigate this, quartz was used to initiate an inflammatory response in two different models. LÄS MER