Sökning: "SPCR"

Hittade 2 avhandlingar innehållade ordet SPCR.

  1. 1. Kinetics of HIV-1 drug resistance mutations in vivo

    Författare :Veronica Svedhem Johansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HIV-1; anti-retroviral therapy; drug resistance; therapy failure; rebound; persistence; wildtype virus; SPCR; minor population;

    Sammanfattning : Antiretroviral therapy (ARV) exert a selective pressure on HIV-1 and may select viral drug resistant strains which have competitive advantage in the presence of the drug. Knowledge about the appearance and disappearance of these mutations is important when choosing ARV. LÄS MER

  3. 2. Detection and significance of drug-resistant HIV-1 minor populations

    Författare :Tobias Bergroth; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HIV-1; antiretroviral treatment; resistance; M184I V; minor populations; selective real-time PCR;

    Sammanfattning : The human immunodeficiency virus (HIV) is the cause of the HIV/AIDS pandemic affecting millions of people around the world. Treatment with antiretroviral drugs, if used properly, leads to a dramatic decrease in virus production in the patient and prevents the onset of AIDS. LÄS MER