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Visar resultat 1 - 5 av 32 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Relative biological effectiveness in proton therapy: accounting for variability and uncertainties

   Författare :Jakob Ödén; Iuliana Toma-Dasu; Kjell Eriksson; Radhe Mohan; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; proton therapy; relative biological effectiveness; linear energy transfer; proton track-end optimisation; radiation-induced toxicity; Medical Radiation Physics; medicinsk strålningsfysik;

   Sammanfattning : Radiation therapy is widely used for treatments of malignant diseases. The search for the optimal radiation treatment approach for a specific case is a complex task, ultimately seeking to maximise the tumour control probability (TCP) while minimising the normal tissue complication probability (NTCP). LÄS MER

3. 2. Proton plan evaluation : a framework accounting for treatment uncertainties and variable relative biological effectiveness

   Författare :Jakob Ödén; Iuliana Toma-Dasu; Kjell Eriksson; Pawel Olko; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Proton therapy; Relative biological effectiveness; Robustness evaluation; Plan selection; Medical Radiation Physics; medicinsk strålningsfysik;

   Sammanfattning : .... LÄS MER

4. 3. Radiation-induced apoptosis in human lymphocytes : studies on expression, function and effects of different radiation qualities

   Författare :Annelie Meijer; Fabrizio Palitti; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Apoptosis; clonogenic survival; growth factors; chromosomal aberrations CA ; low dose-rate LDR ; linear energy transfer LET ; relative biological effectiveness RBE ; radio sensitivity; ataxia telangiectasia A-T ; Physical Biology; fysikalisk biologi;

   Sammanfattning : We are constantly exposed to radiation. Radiation causes damage to our cells. By the removal of damaged and unwanted cells, apoptosis is considered to be one of the most indispensable defence processes for a multi-cellular organism. LÄS MER

5. 4. Plant pathogen defense: Signalling, resistance and cell death

   Författare :Oskar N. Johansson; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Pseudomonas; cell death; pathogens; plant defense; hypersensitive response; glycolipid; reactive oxygen species; blumeria graminis; erysiphe pisi;

   Sammanfattning : Pathogenic microorganisms are present everywhere in nature and infect both animals and plants. Phytopathogenic microorganisms cause diseases on plants, and are responsible for crop loss amounting in the order billions of dollars annually. LÄS MER

7. 5. Comparative Treatment Planning in Radiotherapy and Clinical Impact of Proton Relative Biological Effectiveness

   Författare :Jonas Johansson; Bengt Glimelius; Anders Montelius; Tony Lomax; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Radiotherapy; Comparative studies; Breast cancer; hypopharyngeal cancer; rectal cancer; Proton RBE; Onkologi; Oncology; Onkologi;

   Sammanfattning : The development of new irradiation techniques is presently a very active field of research with increased availability of more sophisticated modalities such as intensity modulated photons (IMRT), protons and light ions. The primary aim of this work is to evaluate if the dose-distributions using IMRT and protons contribute to clinical advantages. LÄS MER