Sökning: "Pleckstrin Homology PH domain"

Hittade 4 avhandlingar innehållade orden Pleckstrin Homology PH domain.

  1. 1. Characterization of specific domains of the cellulose and chitin synthases from pathogenic oomycetes

    Författare :Christian Brown; Vincent Bulone; Carol Munro; KTH; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Cellulose biosynthesis; chitin biosynthesis; cellulose synthase genes; chitin synthase genes; oomycetes; Saprolegnia monoica; Microtubule Interacting and Trafficking MIT domain; Pleckstrin Homology PH domain; Biotechnology; Bioteknologi;

    Sammanfattning : Some oomycetes species are severe pathogens of fish or crops. As such, they are responsible for important losses in the aquaculture industry as well as in agriculture. Saprolegnia parasitica is a major concern in aquaculture as there is currently no method available for controlling the diseases caused by this microorganism. LÄS MER

  2. 2. Molecular biology of Brouton's tyrosine kinase

    Författare :Carl-Magnus Bäckesjö; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :X-linked agammaglobulinemia; XLA; Bruton s tyrosine kinase; Btk; signal transduction; phosphorylation; pleckstrin homology domain; PH; SH2; SH3.;

    Sammanfattning : X-linked agammaglobulinemia (XLA) is caused by an arrest in the B lymphocyte differentiation. XLA patients lack mature B-cells and subsequently antibody production. The defective gene causing XLA is the BTK gene, which codes for the protein Bruton s tyrosine kinase (Btk), a cytoplasmic enzyme related to the Src family of kinases. LÄS MER

  3. 3. Functional characterization of cellulose and chitin synthase genes in Oomycetes

    Författare :Johanna Fugelstad; Vincent Bulone; Carol Munro; KTH; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; cellulose biosynthesis; chitin biosynthesis; cellulose synthase gene; chitin synthase gene; Oomycetes; Phytophthora infestans; Saprolegnia monoica; pleckstrin homology domain; Microbiology; Mikrobiologi;

    Sammanfattning : Some species of Oomycetes are well studied pathogens that cause considerable economical losses in the agriculture and aquaculture industries. Currently, there are no chemicals available that are environmentally friendly and at the same time efficient Oomycete inhibitors. LÄS MER

  4. 4. Evolution and transcriptional regulation of Kindlins

    Författare :Ammad Khan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Kindlins are relatively newly discovered focal adhesion proteins. The Kindlin family includes three highly conserved proteins: Kindlin-1, Kindlin-2 and Kindlin-3. All three Kindlins have been shown to interact with Integrin and this interaction plays important role in the functional properties of Kindlins. LÄS MER