Sökning: "Platelet derived growth factor receptor"

Visar resultat 6 - 10 av 96 avhandlingar innehållade orden Platelet derived growth factor receptor.

1. 6. Pericyte recruitment and functions in vivo. Studies of platelet-derived growth factor-B deficient embryos

   Författare :Mats Hellström; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mouse; gene targeting; platelet-derived growth factor; pericyte; vascular smooth muscle; angiogenesis;

   Sammanfattning : A functional vascular system is essential for tissue growth and maintenance, and the circulatory system is therefore the first operational organ of the vertebrate embryo. In conditions of pathological tissue growth, such as tumors, formation of new blood vessels is also required, and it is anticipated that prevention of blood vessel development in those settings might ameliorate the disease progress. LÄS MER

3. 7. Signal transduction via the ß-receptor for platelet-derived growth factor

   Författare :Klaus Hansen; Uppsala universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : .... LÄS MER

4. 8. Regulation of Platelet-Derived Growth Factor Receptor Signaling and its Targeting in Cancer Therapy

   Författare :Haisha Ma; Johan Lennartsson; Håkan Axelson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PDGF; PDGFR; Ras; macropinocytosis; Fer; STAT3; HD-PTP; Cbl; ubiquitination; pericyte; vasculature; tumor; ASKA; Biology with specialization in Molecular Cell Biology; Biologi med inriktning mot molekylär cellbiologi;

   Sammanfattning : Overactivity of platelet-derived growth factor receptor (PDGFR) is a frequent event in many types of solid tumors. Therefore, it is of great importance to uncover the mechanisms that regulate PDGF/PDGFR signalling, to develop efficient inhibitors targeting this pathway. LÄS MER

5. 9. Transcriptional Regulation of the Platelet-Derived Growth Factor B-receptor by p53 Family Members

   Författare :Daniel Wetterskog; Göteborgs universitet; []
   Nyckelord :;

   Sammanfattning : Aims: The platelet-derived growth factor ?-receptor (PDGFRB) is critically involved in embryonic development and has a role in many diseases. In cells, signaling through PDGFRB affects growth, migration and death. LÄS MER

7. 10. Midgut Carcinoid Tumours : New Diagnostic Procedures and Treatment

   Författare :Staffan Welin; Eva T. Janson; Barbro Eriksson; Larry Kvols; Uppsala universitet; []
   Nyckelord :Medicine; Midgut carcinoid tumour; Chromogranin A; Carcinoid heart disease; Survival; Octreotide pamoate; Tyrosine kinase receptors; Platelet derived growth factor receptor; Epidermal growth factor receptor; Medicin;

   Sammanfattning : Midgut carcinoid tumours are rare with an incidence of 0.5-2.1/100 000. The primary tumour is usually small and grows slowly but has almost always set metastases at diagnosis. LÄS MER