Sökning: "Carcinoid heart disease"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden Carcinoid heart disease.

1. 1. Carcinoid heart disease : a clinical, biochemical and morphological study

   Författare :Lennart Lundin; Uppsala universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : .... LÄS MER

3. 2. Midgut Carcinoid Tumours : New Diagnostic Procedures and Treatment

   Författare :Staffan Welin; Eva T. Janson; Barbro Eriksson; Larry Kvols; Uppsala universitet; []
   Nyckelord :Medicine; Midgut carcinoid tumour; Chromogranin A; Carcinoid heart disease; Survival; Octreotide pamoate; Tyrosine kinase receptors; Platelet derived growth factor receptor; Epidermal growth factor receptor; Medicin;

   Sammanfattning : Midgut carcinoid tumours are rare with an incidence of 0.5-2.1/100 000. The primary tumour is usually small and grows slowly but has almost always set metastases at diagnosis. LÄS MER

4. 3. Midgut carcinoid tumours - biochemical and therapeutic aspects

   Författare :Gunnel Westberg; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; carcinoid syndrome; valvular heart disease; 5-HT; chromogranins; octreotide; hepatic arterial embolization;

   Sammanfattning : The biology of human midgut carcinoid tumour was studied experimentally in primary cell culture and clinically in patients with the midgut carcinoid syndrome. In cell cultures, tumour cells had a secretory pattern of 5-HTP, 5-HT and 5-HIAA specific for each tumour indicating individual regulation of synthesis/degradation. LÄS MER

5. 4. Towards Immunotherapy of Midgut Carcinoid Tumors

   Författare :Sofia Vikman; Thomas Tötterman; Valeria Giandomenico; Bengt Widegren; Uppsala universitet; []
   Nyckelord :Immunology; midgut carcinoid; gene expression; immunotherapy; tumor antigen; VMAT-1; T cell; HLA-A*0201-binding peptide; IFNγ; regulatory T cell; Immunologi;

   Sammanfattning : Classical midgut carcinoids belong to neuroendocrine tumors of the gastroenteropancreatic tract (GEP-NETs) and are associated with serotonin overproduction. The term midgut is derived from the tumors’ embryological site of origin: enterochromaffin cells in the lower jejunum, ileum, caecum and the ascending colon. LÄS MER

7. 5. Clinical and immunohistochemical studies of small bowel carcinoid tumours

   Författare :Kalle Landerholm; Johannes Järhult; Nils Wierup; Sture Falkmer; Roland Andersson; Bo Wängberg; Linköpings universitet; []
   Nyckelord :;

   Sammanfattning : Small bowel carcinoid tumours arising from enterochromaffin cells in the jejunum and ileum are neuroendocrine tumours (NETs) characterized by secretion of serotonin, tachykinins and other bioactive substances. These substances may lead to the typical carcinoid syndrome as well as pronounced fibrosis locally and in the heart. LÄS MER