Sökning: "Pharmaceutical R D"

Visar resultat 16 - 20 av 20 avhandlingar innehållade orden Pharmaceutical R D.

1. 16.

   Författare :Maria Elmquist; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NPD processes; innovation; absorptive capacity; R D; innovative capabilities; generative capacity.; innovative concepts;

   Sammanfattning : Enabling innovation Exploring the prerequisites for innovative concepts in R&DMaria ElmquistDivision of Project ManagementChalmers University of TechnologyAbstractThis thesis deals with the prerequisites for innovative concepts to impact NPD processes in large firms R&D. Based on empirical data, mainly from the automotive and pharmaceutical industries, the aim is to shed light on the actual practices of early phases of NPD, investigating the interface between innovative activities and planned development projects. LÄS MER

3. 17. When Innovation Is Not Enough

   Författare :Jonatan Freilich; Mats Engwall; Katarina Nordqvist; Anette Hallin; Paul Nightingale; KTH; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; established firm challenge; technology change; R D management; architectural process innovation; drug development; biomarkers; Industriell ekonomi och organisation; Industrial Engineering and Management;

   Sammanfattning : Innovation is not always enough. In the beginning of the 2000s established pharmaceutical firms had developed several drugs, yet these new products were far too few. Patents of many blockbuster drugs were to soon expire and substantial profit would then be lost. LÄS MER

4. 18. The value of evaluating and implementing pharmaceuticals

   Författare :Kasper Johannesen; Martin Henriksson; Lars-Åke Levin; Magnus Janzon; Katarina Steen Carlsson; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Pharmaceuticals are a central part of high-quality health care and a resource for improving population health. However, high prices set by private companies who develop and own the rights to new pharmaceuticals question the value that they contribute to the health care system. LÄS MER

5. 19. Long acting local anaesthetics - a study in rats

   Författare :Henrik Dyhre; Anestesiologi och intensivvård; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; in vivo and effect kinetics; Comparison of in vitro; Neuro toxicity; Infraorbital nerve block; Sciatic nerve block; Lipid depot formulation;

   Sammanfattning : Local anaesthetics provide excellent pain relief after central and peripheral nerve blocks. However, in many clinical situations there is an insufficient duration of action to allow effective treatment of long-term pain with single injection techniques. This problem became the focus of the present studies. LÄS MER

7. 20. Optimisation of Clinical Trials using Bayesian Decision Theory

   Författare :Sebastian Jobjörnsson; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; decision theory; drug regulation; ; Bayesian statistics; subgroup analysis; clinical trials; health economics; multiple testing; decision theory;

   Sammanfattning : A decision maker confronted with the task of designing a clinical trial has to consider a multitude of aspects. Large trials lead to more evidence,which in turn makes it less likely that harmful decisions are taken when deciding on future treatments for patients. LÄS MER