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Visar resultat 16 - 20 av 663 avhandlingar som matchar ovanstående sökkriterier.

  1. 16. Streptococci and Platelets - A Study of Host-Pathogen Interaction Dynamics

    Författare :Lisbeth Svensson; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; host-pathogen interactions; bacterial entrapment; disaggregation; aggregation; platelet activation; Streptococci;

    Sammanfattning : Invasive infections remains one of the leading causes of death due to infections over the world, and efficient treatment remains elusive. One of the major causes of sepsis and other invasive infections is pathogenic streptococci that cause a wide range of clinical manifestations in humans. LÄS MER

  3. 17. Diving into short linear motifs : Large-scale identification of endogenous and host-pathogen protein-protein interactions and further characterized by deep mutational scanning

    Författare :Caroline Benz; Ylva Ivarsson; Birthe B. Kragelund; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein-protein interactions; short linear motif; endogenous interactions; host-pathogen; viral hijacking; deep mutational scanning; Biokemi; Biochemistry;

    Sammanfattning : Short linear motifs (SLiMs) are protein-protein interaction sites that play an essential role in distinct cellular processes. Those interactions are challenging to capture by common high-throughput methods. LÄS MER

  4. 18. Comparative analysis of pathogen occurrence in wastewater : management strategies for barrier function and microbial control

    Författare :Jakob Ottoson; Bengt Hultman; Roland Schertenleib; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; bacteria; parasites; treatment; Water engineering; Vattenteknik;

    Sammanfattning : This project was initiated to fill knowledge gaps on the occurrence of pathogens in different streams of wastewater, e.g. greywater and domestic wastewater. LÄS MER

  5. 19. A holistic approach to host-pathogen interactions : Detecting the large to unravel the small

    Författare :Kristoffer Sjöholm; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mass spectromery; Proteomics; Host-pathogen interactions; Sepsis;

    Sammanfattning : Sepsis is one of the leading causes of mortality and morbidity in the world, and is an overreaction by the immune system due to pathogen invasion of the bloodstream. The interactions, particularly the protein interactions, between the host and pathogen are fundamental for the outcome of the disease. LÄS MER

  7. 20. Pathogen-mediated selection in the immune system of rodents : Exploring selection targets, functional effects and trade-offs

    Författare :Mridula Nandakumar; Funktionell zoologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; pathogen-mediated selection; bank voles; Myodes glareolus; immune system; balancing selection; immune response; rodents; positive selection; transcriptomics;

    Sammanfattning : Pathogens cause disease and play an important role in shaping evolution of the host immune system. They create pressure on host immunity to evolve in numerous ways, most commonly by increasing divergence between species (positive selection) or increasing polymorphisms within a population (balancing selection). LÄS MER