Sökning: "O-antigen"

Visar resultat 11 - 15 av 32 avhandlingar innehållade ordet O-antigen.

  1. 11. Structural studies of bacterial polysaccharides using N.M.R. spectroscopy and mass spectrometry

    Författare :Johan Lindberg; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : This work describes the structural studies of the capsularpolysaccharides from Streptococcus pneumoniae type 18F and 7B,Alcaligenes ATCC 31961 (S-194), and the O-antigen polysaccharidefrom Vibrio cholerae 0:3.The principal methods used in these studies were ID and 2D n.m.r. LÄS MER

  3. 12. Characterization of Shigella dysenteriae type 1 hybrid vaccine candidates

    Författare :Inger Fält; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Shigellae is endemic in many developing countries in the world and a major cause of childhood diarrheal morbidity and mortality. Infections caused by Shigella dysenteriae type 1 are particularly severe. LÄS MER

  4. 13. Chemical studies of 0-antigens from Shigella

    Författare :Kurt Petersson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The structure of 13 types of Shigella flexneri O-antigens has been determined, using a N-deacetylation-deamination reaction sequence. The correlation between chemical structures and immunological classification of Shigella flexneri is discussed. LÄS MER

  5. 14. Virulence of Salmonella enterica serovar typhimurium and innate antibacterial host responses

    Författare :Eva Bjur; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Salmonella; LPS; macrophages; NOS; SPI-2; thioredoxin; TrxA; TRAPC;

    Sammanfattning : The bacterial species Salmonella enterica consists of a collection of closely related enteric bacteria giving rise to diverse diseases in a wide range of hosts. In the murine infection model Salmonella enterica serovar Typhimurium (S. Typhimurium) causes an invasive disease which in many aspects resembles human typhoid fever. LÄS MER

  7. 15. Synthesis of some oligosaccharide fragments of biological and chemical interest using thioglycosides

    Författare :Christer Hällgren; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic Chemistry; organisk kemi;

    Sammanfattning : This thesis describes the synthesis of oligosaccharide derivatives corresponding to the repeating unit of the O-antigen from two different bacteria, Shigella dysenteriae type 1 and Salmonella thompson serogroup Ci, and fragments thereof. Synthesis of a decasaccharide of chemical interest for studying carbohydrate dynamics in elongated molecules is also described. LÄS MER