Sökning: "Neurovetenskap"

Visar resultat 16 - 20 av 733 avhandlingar innehållade ordet Neurovetenskap.

  1. 16. Functional consequences of dopaminergic degeneration : Clinical and experimental studies using a novel stabilizer of dopaminergic systems

    Författare :Anna Ekesbo; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Parkinson s disease; positron emission tomography; 6-OHDA; MPTP; dyskinesia; dopaminergic degeneration; - -OSU6162; Neurovetenskap; Neurology; Neurologi; Neurology; neurologi;

    Sammanfattning : Since the introduction of levodopa for the treatment of Parkinson's disease (PD) 30 yearsago, the emergence of motor complications, such as levodopa-induced dyskinesias (LID), hasbeen a major clinical problem in advanced stages of the disease. Clinical and preclinical studieshave revealed a number of functional changes in the dopaminergic system that may be ofimportance for the emergence of LIDs. LÄS MER

  3. 17. Serotonergic and steroidal influences on impulsive behaviour in rats

    Författare :John L. Evenden; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; impulsivity; serotonin; 8-OH-DPAT; DOI; steroid; testosterone; Neurovetenskap; Neurology; Neurologi; medicinsk farmakologi; Medical Pharmacology;

    Sammanfattning : Impulsiveness is a trait contributing to the personality of all human beings to a greater and lesser extent. In a pathological form it can lead to impulsive behaviour which is an important component of many psychiatric and neurological disorders. LÄS MER

  4. 18. Evolution and Pharmacology of Neuropeptide Y Receptors, Implications for vertebrate genome duplications

    Författare :Robert Fredriksson; Susanne Holmgren; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Evolution; tetraploidizations; G-protein coupled receptor; neuropeptide Y; zebrafish; chicken; rainbow trout; lamprey; genome duplications; peptide YY; pancreatic polypeptide; Neurovetenskap; Neurology; Neurologi; medicinsk farmakologi; Medical Pharmacology;

    Sammanfattning : The Y receptors comprise a family of evolutionarily related receptors belonging to the superfamily of G-protein coupled receptors (GPCR). Their natural ligands are in mammals neuropeptide Y (NPY), peptide YY (PYY) and pancreatic polypeptide (PP). LÄS MER

  5. 19. Platelet monoamine oxidase : From genetic regulation to behavior

    Författare :Håkan Garpenstrand; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; monoamine oxidase; platelet; personality; CNS; serotonin; dopamine; Neurovetenskap; Neurology; Neurologi; medicinsk farmakologi; Medical Pharmacology;

    Sammanfattning : Genetic and environmental factors contribute to the development of personality and vulnerability forpsychiatric disorders. The activity of monoamine oxidase in platelets (trbc-MAO), which is mainlygenetically determined, correlates to personality traits such as sensation-seeking and impulsiveness, andlow trbc-MAO activity is more common in patients with type 2 alcoholism. LÄS MER

  7. 20. PET applications in schizophrenia : Functional and pharmacological dopamine studies

    Författare :Ola Gefvert; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Schizophrenia; PET; dopamine synthesis rate; dopamine D2 receptor occupancy; atypical antipsychotics; quetiapine; risperidone microsphere depot; Neurovetenskap; Neurology; Neurologi; Psychiatry; psykiatri;

    Sammanfattning : Schizophrenia is a group of disorders with a worldwide lifetime prevalence of 0.85%. Thefunctional outcome of the disorder seem stable from the first systematic outcome studies to thepresent day, and vary only with changes in diagnostic criteria. LÄS MER