Sökning: "NATURVETENSKAP Biologi Cell- och molekylärbiologi Neurobiologi"
Visar resultat 1 - 5 av 20 avhandlingar innehållade orden NATURVETENSKAP Biologi Cell- och molekylärbiologi Neurobiologi.
1. Insulin Signalling in Human Adipocytes and its Interplay with beta-Adrenergic Control of Lipolysis
Sammanfattning : The prevalence of obesity has over the last 40 years nearly tripled and obesity is one of the major risk factors of developing type 2 diabetes. Type 2 diabetes was formerly called adultonset diabetes but today, probably due to the rise in childhood obesity, it is also seen in children and adolescents. LÄS MER
2. Imaging the molecular pathways of neurodegeneration : New pathologies of SCA7
Sammanfattning : Spinocerebellar Ataxia type 7 (SCA7) is a genetic neurodegenerative disease with lethal outcome that affects the cerebellum and retina of patients. This thesis focuses on characterising molecular pathological pathways that cause toxicity and cell death in SCA7. LÄS MER
3. Identification and characterization of nuclear envelope protein interactions
Sammanfattning : The Nuclear envelope which surrounds the chromatin of eukaryotic cells contains more than a hundred transmembrane proteins. Mutations in some genes encoding nuclear envelope proteins give rise to human diseases including neurological disorders. The function of many nuclear envelope proteins is not well established. LÄS MER
4. Site and Mechanism of Action of Resin Acids on Voltage-Gated Ion Channels
Sammanfattning : Voltage-gated ion channels are pore-forming membrane proteins that open or close their gates when the voltage across the membrane is changed. They underlie the electrical activity that enables the heart to pump blood and the brain to receive and send signals. LÄS MER
5. Multifaceted roles of the transmembrane nuclear envelope protein, Samp1
Sammanfattning : The eukaryotic nuclear envelope (NE), separates the nucleoplasm from cytoplasm and is made up of two concentric lipid membranes, the outer and the inner nuclear membranes (ONM and INM), the nuclear pore complexes (NPCs) and an underlying filamentous nuclear lamina. The INM contains hundreds of unique transmembrane proteins of which only a handful have been characterized. LÄS MER