Sökning: "gut immune cell distribution"

Visar resultat 1 - 5 av 9 avhandlingar innehållade orden gut immune cell distribution.

  1. 1. Gut Feelings - From Brain to Gut and from Lumen to Gut

    Författare :Xiaowen Cheng; Neurogastroenterologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Enteric nervous system; cerebral ischemia; galectine-3; tuft cell; CGRP; CCK; GLP-1; 5HT; PYY;

    Sammanfattning : Part 1: From Brain to GutThe brain is an organ with a high energy requirement. To meet this demand, the brain needs a continuous and well-regulated blood supply. In situations where the brain, or parts of the brain, does not receive sufficient blood flow injury arise. LÄS MER

  3. 2. Intestinal Gene Expression Profiling and Fatty Acid Responses to a High-fat Diet

    Författare :Jonathan Cedernaes; Helgi B Schiöth; Robert Fredriksson; Anders Jacobsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adhesion GPCR; delta-5 desaturase; delta-6 desaturase; desaturase index; Diet-induced obesity; estimated desaturase activity; fatty acid composition; gas chromatography; gastrointestinal tract; G-protein coupled receptor; high-fat diet; intestine; linoleic acid; liver; mRNA expression; palmitoleic acid; plasma; phospholipids; proximodistal; RT-qPCR; solute carrier; SCD-1; SCD-16; SCD-18; stearoyl-CoA desaturase; subcutaneous adipose tissue; subsection; triacylglycerols.; Medical Genetics; Medicinsk genetik; Nutrition; Nutrition; Näringslära; Nutrition;

    Sammanfattning : The gastrointestinal tract (GIT) regulates nutrient uptake, secretes hormones and has a crucial gut flora and enteric nervous system. Of relevance for these functions are the G protein-coupled receptors (GPCRs) and the solute carriers (SLCs). LÄS MER

  4. 3. Inflammatory Reactions in Peritonitis and Malignant Obstructive Jaundice : Clinical and Experimental Studies with Special Emphasis on the Cellular Immune Response

    Författare :Johanna Österberg; Ulf Haglund; Mikael Ljungdahl; Roland Andersson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; CLP; sepsis; peritonitis; bacterial translocation; malignant obstructive jaundice; Linomide; COX inhibitor; SC-236; indometacin; T lymphocyte; macrophage; mucosa; MLN; gut immune cell distribution; mucosal injury; cytokines; TNF-α; IL-6; IL-10; endotoxin; caspase-3; apoptosis; Kirurgi; Surgery; Kirurgi;

    Sammanfattning : Patients with peritonitis or malignant obstructive jaundice (HPB+) have an increased morbidity and mortality due to sepsis. An altered cell-mediated immunity in the intestinal mucosa might promote gut barrier failure, increased endotoxin and cytokine release and bacterial translocation (BT) in these conditions. LÄS MER

  5. 4. Human intestinal T lymphocytes : a comparative analysis of phenotype and function in normal and inflamed mucosa

    Författare :Silvia Melgar; Nadine Cerf-Bensussan; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human intestinal mucosa; intraepithelial lymphocyte; lamina propria lymphocyte; γδ T cell; regulatory T cell; cytotoxicity; cytokine; basal lymphoid aggregate; ulcerative colitis; Crohn s disease;

    Sammanfattning : The epithelial lining of the gut must allow immediate contact with beneficial components as nutrients and normal microflora. At the same time it runs the constant risk of attack from pathogenic microbes and noxious agents. LÄS MER

  7. 5. Acute pancreatitis - Cellular response and dynamic inflammatory changes

    Författare :Marwan Dib; Lund Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Veterinary medicine:surgery; inflammatory mediators.; adhesion molecules; endothelial barrier dysfunction; inflammatory response; mast cell; abdominal sepsis; Acute pancreatitis; physiology; pathology; clinical studies; Veterinärmedicin:kirurgi; fysiologi; patologi; kliniska studier;

    Sammanfattning : Acute pancreatitis (AP) is a common disorder where underlying mechanisms for the local initiating events in the pancreas, the systemic dissemination of the inflammatory response and the remote organ dysfunction still are unclear. The aim of the present study was to further characterize the dynamics and sequence of the immune response in AP, and to determine the cellular origin of the initiating events. LÄS MER