Sökning: "interferon-γ"
Visar resultat 1 - 5 av 39 avhandlingar innehållade ordet interferon-γ.
1. Monoclonal antibodies to human interferon-α and interferon-γ : Characterization and application with focus on interferon-γ as a T cell cytokine
Sammanfattning : The major functions of the immune system are to combat infections and to control that normal auto-immunity does not turn into auto-aggression. Antibodies, together with T cell receptors and MHC molecules, dictates the immunological specificity. LÄS MER
2. Immunological aspects of latent tuberculosis infection during pregnancy
Sammanfattning : Pregnancy-induced immune modulation might lead to reactivation of latent tuberculosis infection (LTBI). This thesis explores aspects of immune-based LTBI diagnostics and how pregnancy affects the immune control of Mycobacterium tuberculosis (Mtb) infection. We studied a prospective cohort of women recruited during pregnancy in Ethiopia. LÄS MER
3. Experimental brain tumors, dendritic cells and immunotherapy
Sammanfattning : Malignant astrocytomas are the most common primary tumors of the adult central nervous system. Surgical resection of tumor mass in combination with radiotherapy and chemotherapy is only palliative and there is a clear need for new and more effective therapeutic strategies. LÄS MER
4. Mesenchymal stromal cells in malignant glioma - Functions and therapeutic potential
Sammanfattning : The most common malignant brain tumor in adults is a glioma called glioblastoma multiforme (GBM). About 300 persons are diagnosed with GBM every year in Sweden. Unfortunately, it is also the most aggressive brain tumor and as of today, it is not possible to cure it. LÄS MER
5. Exploration of Conditions Affecting Cytokine Production in Experimental Type 1 Diabetes Mellitus
Sammanfattning : Cytokines are soluble signalling mediators within the immune system, and have been shown to be of importance in the development of type 1 diabetes (T1D). This thesis studied the production of cytokines in experimental models of T1D and during transplantation of insulin-producing islets of Langerhans. LÄS MER