Sökning: "Maria Jenmalm"
Visar resultat 16 - 20 av 22 avhandlingar innehållade orden Maria Jenmalm.
16. Early life cytokines, viral infections and IgE-mediated allergic disease
Sammanfattning : Background: The reasons why some individuals become IgE-sensitised and allergic are largely unknown, though genetic- and early life environmental factors seem to be of importance.Objective: The overall aim of this thesis was to investigate the relationship between IgE-sensitisation and allergic disease, viral infections, genetic markers and early life cytokines. LÄS MER
17. Immune regulation at the foetal-maternal interface; implications for healthy and complicated pregnancies
Sammanfattning : For a successful pregnancy, the maternal immune system must acquire tolerance towards the paternal antigens present in the semi-allogeneic foetus. This tolerance is mainly established locally at the foetal-maternal interface, where foetally-derived trophoblasts invade the maternal endometrium (called decidua during pregnancy) and come in close proximity to maternal immune cells. LÄS MER
18. Toxicoproteomics, from finding molecular targets to evaluating the impact on human health
Sammanfattning : The exposome refers to all exposures, including exposures to chemicals, that an individual may encounter over the whole life, from conception to death, that influence the individual’s health. To date, over 200,000 chemicals have been registered under the legislative framework of the European Union. LÄS MER
19. Studies of barrier function in patients with ulcerative colitis and pouchitis
Sammanfattning : Background and aim: The cause of ulcerative colitis (UC) is largely unknown. However, there is a presumed genetic component to susceptibility and altered intestinal barrier function has been implicated in the pathophysiology of ulcerative colitis. LÄS MER
20. Immune regulation during pregnancy in relation to allergy and in women undergoing in vitro fertilization
Sammanfattning : During pregnancy, the fetus expresses both maternal and paternal antigens. To the mother, the paternal antigens are foreign, providing her immune system with an interesting challenge. The fact that the fetus is not normally attacked and rejected implies that mechanisms of tolerance must exist. LÄS MER