Sökning: "Lina Emilsson"

Hittade 2 avhandlingar innehållade orden Lina Emilsson.

1. 1. Detection of Differentially Expressed Genes in Alzheimer's Disease : Regulator of G-protein Signalling 4: A Novel Mediator of APP Processing

   Författare :Lina Emilsson; Elena Jazin; Karoly Mirnics; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Alzheimer s disease; RGS4; ITPKB; RAB3A; APP processinig; Biology; Biologi;

   Sammanfattning : Alzheimer’s disease is a neurodegenerative disease characterised by progressive memory deterioration and cognitive impairment. Pathological hallmarks are extracellular senile plaques, neurofibrillary tangles and neuron loss. Senile plaques are produced through altered processing of the membrane-bound protein APP. LÄS MER

3. 2. Translational research of the quaking gene : Focusing on the conjunction between development and disease

   Författare :Bryn Farnsworth; Lina Emilsson; Roman Chrast; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; QKI; glia; oligodendrocyte; Alzheimer s; schizophrenia; zebrafish; statistics; morpholino; Biologi med inriktning mot evolutionär organismbiologi; Biology with specialization in Evolutionary Organismal Biology;

   Sammanfattning : Quaking (QKI) is an RNA binding protein involved in the post-transcriptional regulation of gene expression. Originally identified as the cause of hypomyelination in a mouse mutant, it has since been consistently implicated in a wide range of neurological diseases. LÄS MER