Sökning: "RGS4"

Hittade 2 avhandlingar innehållade ordet RGS4.

1. 1. Detection of Differentially Expressed Genes in Alzheimer's Disease : Regulator of G-protein Signalling 4: A Novel Mediator of APP Processing

   Författare :Lina Emilsson; Elena Jazin; Karoly Mirnics; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Alzheimer s disease; RGS4; ITPKB; RAB3A; APP processinig; Biology; Biologi;

   Sammanfattning : Alzheimer’s disease is a neurodegenerative disease characterised by progressive memory deterioration and cognitive impairment. Pathological hallmarks are extracellular senile plaques, neurofibrillary tangles and neuron loss. Senile plaques are produced through altered processing of the membrane-bound protein APP. LÄS MER

3. 2. In vitro and postmortem studies of the brain opioid system : association to opiate dependence

   Författare :Parisa Zarnegar; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Opioid system; brain; gene expression; amygdala; hippocampus; opiate dependence;

   Sammanfattning : Opioids such as heroin are highly addictive illicit drugs. The μ opioid receptor (MOR) plays a central role in mediating the effects of opiates and related opioid. LÄS MER