Avancerad sökning

Hittade 5 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Novel strategies to improve thrombolysis therapy after stroke

    Författare :Kajsa Arkelius; Neurokirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ischemic stroke; thrombolysis; rt-PA; MMP-9; ERK1 2; LOX-1; BBB;

    Sammanfattning : .... LÄS MER

  3. 2. Human 15-lipoxygenase-1 and telomerase gene expression in cancer and inflammation

    Författare :Cheng Liu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Human 15-lipoxygenase type 1 (15-LOX-1) is an enzyme that catalyzes the oxygenation of free or membrane-bond polyunsaturated fatty acids containing at least one bis-allylic methylene moiety. The enzyme has been proposed to be involved in various physiological and pathophysiological activities including inflammation, apoptosis, cell maturation and tumorigenesis. LÄS MER

  4. 3. Studies on the regulation and function of lipoxygenases in Hodgkin lymphoma

    Författare :Hongya Han; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Hodgkin lymphoma (HL) is a unique entity among the lymphomas, with a minority of malignant Hodgkin and Reed-Sternberg (H-RS) cells surrounded by a broad range of infiltrating cells. The infiltration of certain inflammatory cells has been reported to predict prognosis of the disease. LÄS MER

  5. 4. Allergic airway disease : studies on diesel exhaust exposures, oxylipins and antioxidants

    Författare :Nirina Larsson; Annelie Behndig; Leif Bjermer; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Asthma; allergic rhinits; diesel exhaust; airway inflammation; oxylipins; metabolomics; antioxidants; SVCT2; bronchoscopy; lungmedicin; Lung Medicine;

    Sammanfattning : Allergic airway disease, i.e. allergic rhinitis (AR) and asthma, is a common health problem. The prevalence is increasing in most countries of the world. LÄS MER

  7. 5. Immune responses against tumors controlled by the actin cytoskeleton : lessons from primary immunodeficiencies

    Författare :Joanna Sara Kritikou; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The actin cytoskeleton and its regulators are vital for cellular processes such as cell motility and immune synapse formation. In this study, the aim was to dissect the role of two of those regulators, WASp and MKL1, in immune cells and their role in tumorigenesis. LÄS MER