Sökning: "Gallsyror"

Hittade 2 avhandlingar innehållade ordet Gallsyror.

1. 1. Understanding the molecular mechanisms of bile acid receptor activation for the treatment of human liver disease

   Författare :Samer Al-Dury; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicinska sjukdomar; Gastroenterologi och hepatologi; FXR; IBAT; Gallsyror; Obesitas; Gallstenar;

   Sammanfattning : Farnesoid X receptor (FXR) is a nuclear transcription factor that is activated by bile acids and regulates bile acid homeostasis, glucose and lipid metabolism. FXR activation by a ligand has been identified as a therapeutic modality for a range of liver and metabolic diseases. LÄS MER

3. 2. Gastroesophageal reflux disease - complications and prognostic aspects

   Författare :Dan Falkenback; Lund Kirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gastroesophageal reflux disease; Barrett s esophagus; natural course; GERD; Adenocarcinoma; prognosis; biomarkers;

   Sammanfattning : This thesis investigates several aspects on gastroesophageal reflux disease (GERD) and associated complications as Barrett’s esophagus and esophageal adenocarcinoma. I. To clarify the natural course of GERD, a pH-metry verified cohort was re-evaluated after 20 years. The course of GERD may well be progressive. LÄS MER