Sökning: "Fluorescence recovery of photobleaching"

Visar resultat 11 - 15 av 19 avhandlingar innehållade orden Fluorescence recovery of photobleaching.

1. 11. Structure Dynamics and Heterogeneity in Soft Materials Determined by FRAP

   Författare :Joel H Hagman; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Soft materials; Fluorescence recovery after photobelaching; Confocal microscopy; Heterogeneity; Structure dynamics;

   Sammanfattning : A common interest in industry today is to be able to control the mass transport inside soft (bio) materials in order to tailor both release and uptake of substances. Most of the materials used are heterogeneous, quite often multiphase or compound materials and often undergo dynamic changes; it is therefore important to have control over the local microstructure in order to tailor the macroscale properties. LÄS MER

3. 12. The contribution of proteins and lipids to COPI vesicle formation and consumption

   Författare :Fredrik Kartberg; Göteborgs universitet; []
   Nyckelord :ARF1; COPI; ARFGAP; vesicle; fusion; diffusion;

   Sammanfattning : In the secretory pathway, movement of proteins between compartments occurs through small (50-100 nm) vesicles. The coat of COPI vesicles is composed the small GTPase ARF1 and the large coatomer complex. In the secretory pathway, these vesicles mediate Golgi-to-ER and intra-Golgi transport. LÄS MER

4. 13. Biophysical studies of cell membrane receptors for the growth factors PDGP and EGF : Aspects on lateral and aggregation

   Författare :Pia Ljungquist-Höddelius; Carl-Henrik Heldin; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : When extracellular growth factors bind to their specific cell surface receptors, they elicit a cascade of biochemical events, including tyrosine kinase-mediated phosphorylation and changes in intracellular free ca2+, leading to cell differentiation and proliferation. However, direct effects of ligand-binding on the receptors are poorly understood. LÄS MER

5. 14. Modulating the activity of OGG1 using small molecules to target the oxidative DNA damage response in cancer and inflammation

   Författare :Bishoy M F Hanna; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The production of reactive oxygen species (ROS) is increased in several pathological conditions including cancer and inflammation. Multiple lines of evidence suggest that ROS are involved in signaling events that promote tumorigenesis and inflammatory responses. LÄS MER

7. 15. Caveolae associated proteins and how they effect caveolae dynamics

   Författare :Björn Morén; Richard Lundmark; Volker Haucke; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Caveolae; caveolin; EHD2; cavin; microdomain; microscopy; TIRF; AFM; medicinsk biokemi; Medical Biochemistry;

   Sammanfattning : Caveolae are a type of invaginated membrane domain that has been shown to be involved in several disease states, including lipodystrophy, muscular dystrophies and cancer. Several of these diseases are caused by the lack of caveolae or caveolae-related signaling deficiencies in the tissues in which the caveolar domain are abundant such as lung, adipose, muscle and their related endothelial cells. LÄS MER