Sökning: "ARF1"

Visar resultat 1 - 5 av 6 avhandlingar innehållade ordet ARF1.

  1. 1. Effects of ARF1 and phospholipase D on the assembly and secretion of apoB-100 containing lipoproteins

    Författare :Lennart Asp; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :; ApoB; ARF1; Phospholipase D; Lipoproteins; VLDL; Lipid droplets.;

    Sammanfattning : Hydrophobic insoluble lipids such as triglycerides and cholesterol ester are transported in spherical, water-soluble molecular complexes called lipoproteins. Lipoproteins are secreted mainly from the liver and intestine into the plasma for distribution to peripheral tissues. LÄS MER

  2. 2. The contribution of proteins and lipids to COPI vesicle formation and consumption

    Författare :Fredrik Kartberg; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :ARF1; COPI; ARFGAP; vesicle; fusion; diffusion;

    Sammanfattning : In the secretory pathway, movement of proteins between compartments occurs through small (50-100 nm) vesicles. The coat of COPI vesicles is composed the small GTPase ARF1 and the large coatomer complex. In the secretory pathway, these vesicles mediate Golgi-to-ER and intra-Golgi transport. LÄS MER

  3. 3. Functional characterization of the secretory pathway and the role of COPI vesicles

    Författare :Johan Hiding; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :Golgi; Phosphoinositides; Fusion; COPI; ARF1; Proteomics; ER;

    Sammanfattning : In the secretory pathway, proteins synthesized in the endoplasmatic reticulum move through the Golgi apparatus in a cis-to-trans direction and then sorts into different types of vesicles at the trans-Golgi network. How intracellular transport takes place has been the focus of cell biology research for a long time. LÄS MER

  4. 4. Analysis of Binding Events and Diffusion in Living Cells

    Författare :Markus Elsner; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :COPI; Golgi; Diffusion; Glycosyltransferases; Sorting; Molecular; Crowding;

    Sammanfattning : It is well known that diffusion is the main mode of transport in living cells, but the consequences of diffusion in a complex cellular environment are not generally appreciated. In this thesis, we have investigated several aspects of how diffusion properties influence the observability of cellular binding kinetics and how they can be used to obtain information about the environment of proteins and other molecules. LÄS MER

  5. 5. Understanding the Molecular Basis of Differential Growth during Apical Hook Development

    Författare :Kristoffer Jonsson; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :NATURVETENSKAP; LANTBRUKSVETENSKAPER; NATURAL SCIENCES; AGRICULTURAL SCIENCES;

    Sammanfattning : Plants’ adaptation to their environment often involves change in development, which in many cases involves the establishment of differential growth rates across organs, for instance during phototropic and gravitropic responses. A striking example of differential growth is the formation of the apical hook, a structure that forms to protect the apical meristem as seedlings penetrate through soil. LÄS MER