Sökning: "COPI"
Visar resultat 1 - 5 av 9 avhandlingar innehållade ordet COPI.
1. Functional characterization of the secretory pathway and the role of COPI vesicles
Sammanfattning : In the secretory pathway, proteins synthesized in the endoplasmatic reticulum move through the Golgi apparatus in a cis-to-trans direction and then sorts into different types of vesicles at the trans-Golgi network. How intracellular transport takes place has been the focus of cell biology research for a long time. LÄS MER
2. The contribution of proteins and lipids to COPI vesicle formation and consumption
Sammanfattning : In the secretory pathway, movement of proteins between compartments occurs through small (50-100 nm) vesicles. The coat of COPI vesicles is composed the small GTPase ARF1 and the large coatomer complex. In the secretory pathway, these vesicles mediate Golgi-to-ER and intra-Golgi transport. LÄS MER
3. Vesicle transport in chloroplasts with emphasis on Rab proteins
Sammanfattning : Chloroplasts perform photosynthesis using PSI and PSII during its light-dependent phase. Inside the chloroplast there is a membrane called thylakoid. The thylakoid membranes are an internal system of interconnected membranes that carry out the light reactions of photosynthesis. LÄS MER
4. The quality control of MHC class I antigen presentation
Sammanfattning : Major histocompatibility complex (MHC) class I molecules present antigenic peptides to CD8+ T cells. The peptides are generated by proteasomes in the cytosol, then translocated across the membrane of the endoplasmic reticulum (ER) by the transporter associated with antigen processing (TAP). LÄS MER
5. Mitotic Kinesin-Like Protein 1 (MKLP1/KIF23) in hereditary congenital dyserythropoietic anemia type III and in cancer
Sammanfattning : A hereditary form of autosomal dominant congenital dyserythropoietic anaemiatype III (CDA III) has been reported in four families from Sweden, Argentina, Cuba and USA. CDA III patients might experience signs of mild anaemia and some of them need occasional blood transfusions. LÄS MER