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Visar resultat 21 - 25 av 71 avhandlingar som matchar ovanstående sökkriterier.

  1. 21. Interrogation of drug effects on the lipid composition of single cells and Drosophila brain using ToF-SIMS imaging

    Författare :Thuy Mai Hoang Philipsen; Chalmers tekniska högskola; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Drosophila melanogaster; Keywords: Mass spectrometry imaging; PC12 cell.; ToF-SIMS; zinc deficiency; lipid change; methylphenidate; cocaine; cognition; omega-3 and 6- fatty acids;

    Sammanfattning : Lipids are essential for all living organisms on Earth. The most important function of lipids is that they act as the building blocks of cellular membranes. Lipids consist of polar head groups and non-polar tail groups and assemble into bilayer structures to create cell and organelle membranes. LÄS MER

  3. 22. A molecular chaperone that governs membrane contact sites and lipid metabolism

    Författare :Sergi Tosal Castaño; Sabrina Büttner; W. Mike Henne; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Yeast; nucleus-vacuole junctions; proteostasis; unfolded protein response; fatty acid elongation; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Transmembrane proteins represent almost one third of the total cellular proteome, and the majority of them requires translocation into the endoplasmic reticulum (ER) to be folded, sorted and transported to their final subcellular destination. High translational rates during exponential cell growth result in a massive influx of immature proteins into the ER, requiring rapid and accurate folding. LÄS MER

  4. 23. The specificities of plant enzymes and their effects on the seed oil quality

    Författare :Simon Jeppsson; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : Triacylglycerols, glycerides with three fatty acids, are the chemical constituent of seed oils. The fatty acid composition determines the chemical and physical characteristics of an oil. Conventional vegetable oils contain a few reoccurring fatty acids, but plants can produce several hundreds of different fatty acids. LÄS MER

  5. 24. Peroxisomal and mitochondrial enzymes involved in lipid metabolism : studies on function and regulation

    Författare :Veronika Tillander; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Fatty acids constitute a major part of the energy that we obtain from the diet and are also the principal source for mammals to store energy. To use the incoming or stored fatty acids as energy, the fatty acids needs to be metabolized of which the majority of fatty acids will be degraded by the mitochondrial β-oxidation system that in the end generates energy to the cell in the form of ATP. LÄS MER

  7. 25. Acyl-CoA thioesterases : auxiliary enzymes in peroxisomal lipid metabolism

    Författare :Maria A K Westin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Peroxisomes are small organelles essential for life, which carry out a variety of functions mostly related to lipid metabolism, including α- and β-oxidation as well as the first steps of plasmalogen biosynthesis. Peroxisomal β-oxidation metabolizes many different lipids including very long-chain fatty acids, dicarboxylic fatty acids, branched-chain fatty acids, eicosanoids and certain xenobiotic fatty acids. LÄS MER