Sökning: "nucleus-vacuole junctions"

Hittade 2 avhandlingar innehållade orden nucleus-vacuole junctions.

  1. 1. A molecular chaperone that governs membrane contact sites and lipid metabolism

    Författare :Sergi Tosal Castaño; Sabrina Büttner; W. Mike Henne; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Yeast; nucleus-vacuole junctions; proteostasis; unfolded protein response; fatty acid elongation; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Transmembrane proteins represent almost one third of the total cellular proteome, and the majority of them requires translocation into the endoplasmic reticulum (ER) to be folded, sorted and transported to their final subcellular destination. High translational rates during exponential cell growth result in a massive influx of immature proteins into the ER, requiring rapid and accurate folding. LÄS MER

  3. 2. Cellular remodeling in response to nutrient exhaustion : From membrane contact sites to autophagy

    Författare :Mahsa Ebrahimi; Sabrina Büttner; Cristina Mazzoni; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Aging and longevity; yeast; phosphate restriction; interorganellar communication; autophagy; MVB pathway; NVJs; lipid droplets; nutritional regimes; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Adaptation to fluctuating environments is critical for cellular fitness and survival. Cells need to sense changes in their surroundings and quickly adjust cellular homeostasis and metabolism accordingly. LÄS MER