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Visar resultat 1 - 5 av 8 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Biomonitoring of epichlorohydrin and some related compounds

    Författare :Helena Hindsø Landin; Bo Jönsson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biomarkers; DNA Adducts; Epichlorohydrin; Glycidol; Hemoglobin adducts.; Physical Biology; fysikalisk biologi;

    Sammanfattning : This thesis considers epichlorohydrin (ECH), an important industrial chemical, that has been shown to be a carcinogen in experimental animals. The aim of this work is to improve the scientific basis for risk estimation of ECH and to suggest a reliable biomonitoring method for exposure. LÄS MER

  3. 2. Quantitative analysis of DNA adducts formed by some epoxides of industrial importance

    Författare :Kamila Plná; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :DNA adducts; 32P-postlabelling; cancer; genotoxicity; occupational; epoxides; allyl glycidyl ether; propylene oxide; epichlorohydrin;

    Sammanfattning : The work presented herein has focused on DNA adduct formation by three industrial epoxides, allyl glycidyl ether, propylene oxide and epichlorohydrin. Epoxides, owing to the strained oxirane ring are chemically reactive and can alkylate various sites in DNA. LÄS MER

  4. 3. Engineering and Functionalization of Hemicellulose Hydrogels

    Författare :Weifeng Zhao; Karin Odelius; Ann-Christine Albertsson; Ulrica Edlund; Tina Vermonden; KTH; []
    Nyckelord :Hemicellulose; O-acetyl-galactoglucomannan; hydrogels; stimuli-responsive; aniline tetramer; aniline pentamer; electro-active; conductivity; pH-sensitivity; magnetic field-responsive; micro-gels; swelling; drug delivery.; Fiber- och polymervetenskap; Fibre and Polymer Science;

    Sammanfattning : Hemicellulose is the second most abundant component in wood and is an important renewable resource  that is used in films, paper composites and biofuels.  Hemicelluloses  have  several  advantages,  including  their abundance,  degradability  and  renewability. LÄS MER

  5. 4. Protein-Based Adhesives for Particleboards

    Författare :Sara Khosravi; Mats Johansson; A. A Broekhuis; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Kemi; Chemistry;

    Sammanfattning : The main objective of this study was to elucidate the possibilities to use wheat gluten (WG) as a binder for particleboards, as well as soy protein isolate (SPI). The focus was on the effect of the adhesive formulation and the processing conditions, while the press parameters were kept constant. LÄS MER

  7. 5. Synthesis of Novel Homoserine Analogues - Towards t he Development of Substrate-based Peptide Inhibitors of cAMP-dependent Protein Kinase

    Författare :Anna-Carin Carlsson; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein kinases; protein kinase inhibitors; substrate-based kinase inhibitors; cAMP-dependent protein kinase; kemptide; homoserine; asymmetric -amino acid synthesis; glycine -anion equivalents; Schöllkopf’s bislactim ether; epoxidation; nucleophilic epoxide ring opening; microwave-assisted synthesis;

    Sammanfattning : Protein kinases are enzymes that via phosphorylation of proteins/peptides regulate most aspects of cell functions and physiology. The enzymes transfer a -phosphoryl group from ATP to hydroxyl groups of Ser, Thr and Tyr residues in their substrates. LÄS MER