Sökning: "kemptide"

Hittade 1 avhandling innehållade ordet kemptide.

1. 1. Synthesis of Novel Homoserine Analogues - Towards t he Development of Substrate-based Peptide Inhibitors of cAMP-dependent Protein Kinase

   Författare :Anna-Carin Carlsson; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein kinases; protein kinase inhibitors; substrate-based kinase inhibitors; cAMP-dependent protein kinase; kemptide; homoserine; asymmetric -amino acid synthesis; glycine -anion equivalents; Schöllkopf’s bislactim ether; epoxidation; nucleophilic epoxide ring opening; microwave-assisted synthesis;

   Sammanfattning : Protein kinases are enzymes that via phosphorylation of proteins/peptides regulate most aspects of cell functions and physiology. The enzymes transfer a -phosphoryl group from ATP to hydroxyl groups of Ser, Thr and Tyr residues in their substrates. LÄS MER