Sökning: "ESPI"

Visar resultat 1 - 5 av 6 avhandlingar innehållade ordet ESPI.

  1. 1. Aspects of the Design of Preparative Chromatography for Purification of Antibodies

    Författare :David Karlsson; Avdelningen för kemiteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Kemiteknik och kemisk teknologi; ion-exchange chromatography; adsorption kinetics; gels; model calibration; robustness analysis; optimisation; ESPI; diffusion; steric mass action; Langmuir MPM; antibodies; design; Preparative chromatography; modelling; proteins; Chemical technology and engineering;

    Sammanfattning : The development of biotechnological products is becoming more and more expensive. One type of protein attracting a great deal of attention in the biopharmaceutical industry is antibodies, which was used in this work. LÄS MER

  3. 2. Mechanistic Modelling of Drug Dissolution and Matrix Formulations: Rotating Disc Dissolution, Dissolution in a Stagnant Medium, Swelling and Dissolving Matrix Systems

    Författare :Erik Kaunisto; Avdelningen för kemiteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Rotating Disc; Diffusion; Dissolution; Controlled Release; Hydrophilic matrices; ESPI;

    Sammanfattning : Popular Abstract in Swedish Under årens lopp har människan gjort stora landvinningar inom läkemedelsforskning, vilket har lett fram till avancerade läkemedel som idag tas för givna. Avancerade läkemedel sätter dock höga krav på tillverkarna av läkemedel, vilket har lett till att framtagandet av nya läkemedel är en ganska komplicerad process. LÄS MER

  4. 3. Characterization of the Mechanisms of Drug Release from Polymer-Coated Formulations using Experiments and Modelling

    Författare :Mariagrazia Marucci; Avdelningen för kemiteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; ethyl cellulose; Release mechanism; coating; polymer blend; modelling; ESPI; diffusion; osmotic pumping; SEM; single pellet; CLSM; hydroxypropyl cellulose; multiple-unit release;

    Sammanfattning : The main objectives of the work presented in this thesis were to develop new experimental methods to improve the understanding of the release mechanism from a coated formulation and to develop new mechanistic models to describe the release process for pellets coated with a semi-permeable film. Another aim was to characterize the release mechanism from a formulation coated with films made of a blend of a water-insoluble polymer, ethyl cellulose (EC), and a water-soluble polymer, hydroxypropyl cellulose (HPC). LÄS MER

  5. 4. Combined speckle interferometry and speckle correlation for non-destructive testing

    Författare :Angelica Andersson; Luleå tekniska universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Experimental Mechanics; Experimentell mekanik;

    Sammanfattning : When a sample is studied during loading in a tensile test machine, the sample is often exposed to rigid body motions during loading at the same time as it deforms due to tension. Therefore, the small deformation field is hard, or impossible, to measure when it is overlaid by a large motion. LÄS MER

  7. 5. TV holography and shearography in experimental mechanics

    Författare :Henrik O. Saldner; Luleå tekniska universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Experimental Mechanics; Experimentell mekanik;

    Sammanfattning : TV holography is an optical non-contacting whole field technique to measure deformation. Names as ESPI or Electronic speckle pattern interferometry, Electro-optic holography and Electronic holography are commonly used for this real-time video based interferometric technique. Shearography has become an important tool in non destructive testing. LÄS MER