Sökning: "Dirkjan van Schaardenburg"

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  1. 1. Pathogenetic factors of importance for the development and progression of rheumatoid arthritis

    Författare :Heidi Kokkonen; Solbritt Rantapää-Dahlqvist; Dirkjan van Schaardenburg; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rheumatoid arthritis; cytokines; autoantibodies; isotypes; PTPN22; HLA-SE; reumatologi; rheumatology;

    Sammanfattning : Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by joint inflammation eventually leading to the destruction of cartilage and bone. The aetiopathogenesis is not completely understood, but previous studies have shown that the disease is multifactorial with genetic, environmental and hormonal factors involved. Immune cells, e. LÄS MER