Sökning: "Clinical Trial"

Visar resultat 6 - 10 av 998 avhandlingar innehållade orden Clinical Trial.

1. 6. Safety with Mechanical Chest Compressions in CPR : Clinical studies with the LUCAS™ device

   Författare :David Smekal; Sten Rubertsson; Michael Baubin; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiac arrest; Cardiopulmonary resuscitation; Mechanical chest compressions; Active compression-decompression; Injury; Autopsy; LUCAS; Medicin; Medicine;

   Sammanfattning : Chest compressions in cardiopulmonary resuscitation are of utmost importance although not without a risk. Many injuries are described but the incidence of these is hard to define due to methodological differences. It is strenuous to perform chest compressions and therefore mechanical chest compressions have been looked upon with interest. LÄS MER

3. 7. Localized Prostate Cancer : Results From a Randomized Clinical Trial

   Författare :Anna Bill-Axelson; Lars Holmberg; Bo Johan Norlén; Peter Wiklund; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; prostate cancer; localized; randomized; biopsies; interviews; Kirurgi; Surgery; Kirurgi;

   Sammanfattning : The aims of the thesis were to• explore whether radical prostatectomy is beneficial compared with watchful waiting in survival and disease progression• find possible effect modifiers• evaluate a protocol of multiple biopsies and investigate if men with previous benign prostate biopsies are a group at risk for later prostate cancer• inquire into patients’ and clinicians’ experiences of randomization in order to find out what made this study possible to conduct, and thereby contribute to improve randomization in the futureThe background material was a large randomized clinical trial, the Scandinavian Prostatic Cancer Group Study Number 4, or SPCG-4, which was open for inclusion from February 1989 through December 1999. It comprised 695 men in Sweden, Finland and Iceland who had localized prostate cancer and were randomized to either radical prostatectomy or watchful waiting. LÄS MER

4. 8. Studies on Cervical Artificial Disc Replacement

   Författare :Catarina Marques; Claes Olerud; Anna MacDowall; Martin Skeppholm; Adrian Elmi Terander; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cervical radiculopathy; artificial disc replacement; Orthopaedics; Ortopedi; Neurokirurgi; Neurosurgery;

   Sammanfattning : Artificial disc replacement (ADR) was developed as an alternative to anterior fusion after decompression for cervical degenerative radiculopathy. By preserving motion, it was expected to prevent acceleration of adjacent segment pathology (ASP) associated with fusion, and lead to better clinical outcomes. LÄS MER

5. 9. Disease-Specific Survival in Prostate Cancer Patients : Results from the Scandinavian Prostate Cancer Group (SPCG) Trial No. 5 and Regional Cancer Register Data

   Författare :Rami Klaff; Folke Sjöberg; Eberhard Varenhorst; Gabriel Sandblom; Ove Andrén; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Androgen deprivation treatment; bone metastases; early failure; extent of disease; hormone-naïve; long-term disease-specific survival; low-risk; mortality; quality-of-life; predictors of survival; prostate cancer.;

   Sammanfattning : IntroductionProstate cancer (PCa) is the most common cancer among men in Sweden. The clinical course varies considerably, which makes it difficult to predict the prognosis in the individual case. In order to explore the early as well as the late course of the disease, large study groups and population-based cohorts are necessary. LÄS MER

7. 10. Monitoring Arthritis - Biochemical, Metodological and Clinical Aspects

   Författare :Maria Andersson; Reumatologi och molekylär skelettbiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Monitoring; COMP; CRP; Biomarkers; Rheumatoid Arthritis; Arthritis; Osteoarthritis; Clinical; Diurnal variation;

   Sammanfattning : Arthritides are musculoskeletal diseases, which predominantly affect the joints e.g. osteoarthritis (OA) and rheumatoid arthritis (RA). Modern treatment strategies include early detection and careful monitoring of the disease course. LÄS MER