Sökning: "Peter Wiklund"

Hittade 4 avhandlingar innehållade orden Peter Wiklund.

  1. 1. Regeneration of Peripheral Nerves. The role of protein kinases, with emphasis on neurotrophic factor stimulation

    Författare :Peter Wiklund; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NT-4; NT-3; NGF; MAPK; PKG; PKA; PKC; nodose ganglion; DRG; conditioning effect; neurotrophic factors; protein kinases; peripheral; nerve regeneration; BDNF; GDNF; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

    Sammanfattning : The purpose of this study was to investigate the role of protein kinases in peripheral nerve regeneration, with the use of dorsal root ganglia (DRG) and nodose ganglia explants from adult mice. The effects of neurotrophic factor stimulation and protein kinase inhibition were studied for long (days) and short term (minutes) effects. LÄS MER

  3. 2. Insomnia Symptoms in Chronic Pain : Clinical presentation, risk and treatment

    Författare :Tobias Wiklund; Elena Dragioti; Steven J. Linton; Björn Gerdle; Péter Alföldi; Bjørn Bjorvatn; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : In recent years, chronic and recurrent pain have gained interest as distinct conditions interacting both with peripheral and central parts of the nervous system as well as with the immune system. The risk of getting affected by abnormal pain modulation i.e. LÄS MER

  4. 3. Adipose tissue, the skeleton and cardiovascular disease

    Författare :Peder Wiklund; Peter Nordström; Anna Nordström; Mats Palmér; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Men; women; regional fat mass; bone mineral density; myocardial infarction; osteocalcin; high impact; longitudinal; Epidemiology; Epidemiologi; Epidemiology; epidemiologi;

    Sammanfattning : Cardiovascular disease (CVD) is the leading cause of death in the Western World, although the incidence of myocardial infarction (MI) has declined over the last decades. However, obesity, which is one of the most important risk factors for CVD, is increasingly common. Osteoporosis is also on the rise because of an aging population. LÄS MER

  5. 4. Localized Prostate Cancer : Results From a Randomized Clinical Trial

    Författare :Anna Bill-Axelson; Lars Holmberg; Bo Johan Norlén; Peter Wiklund; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; prostate cancer; localized; randomized; biopsies; interviews; Kirurgi; Surgery; Kirurgi;

    Sammanfattning : The aims of the thesis were to• explore whether radical prostatectomy is beneficial compared with watchful waiting in survival and disease progression• find possible effect modifiers• evaluate a protocol of multiple biopsies and investigate if men with previous benign prostate biopsies are a group at risk for later prostate cancer• inquire into patients’ and clinicians’ experiences of randomization in order to find out what made this study possible to conduct, and thereby contribute to improve randomization in the futureThe background material was a large randomized clinical trial, the Scandinavian Prostatic Cancer Group Study Number 4, or SPCG-4, which was open for inclusion from February 1989 through December 1999. It comprised 695 men in Sweden, Finland and Iceland who had localized prostate cancer and were randomized to either radical prostatectomy or watchful waiting. LÄS MER