Sökning: "CD56 cells"

Visar resultat 6 - 10 av 23 avhandlingar innehållade orden CD56 cells.

1. 6. The therapeutic potential of ex vivo expanded natural killer (NK) cells for immunotherapy of cancer

   Författare :Hayrettin Guven; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Natural killer NK cells; Natural killer-like T NKT cells; Gene transfer; Retrovirus; Good manufacturing practice GMP ; Ex vivo; In vivo; SCID-beige.;

   Sammanfattning : Cell and gene therapy of cancers has received much attention in the past decade. A number of applications of cancer treatment have been developed and used. One of the recent applications is immunotherapy of tumours with human natural killer (NK) cells. LÄS MER

3. 7. Experimental studies of human fetal liver cells : in regard to in utero hematopoietic stem cell transplantation

   Författare :Bim Lindton; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :In utero transplantation; fetal liver cells; mixed lymphocyte culture; CD3; CD56; HLA class II; parvovirus B 19 capsids; corticosteroids; cytotoxic drugs; colony formation.;

   Sammanfattning : Successful in utero hematopoietic stem cell transplantation represents a potential step forward in the management of patients with severe inherited hematological, metabolic and immunological disorders. Animal data from a number of species have demonstrated evidence of engraftment, but to date the only effective in utero transplantations (IUTx) in humans have been performed in fetuses with severe immunodeficiencies, suggesting that the fetal immune system play a vital role in the success or failure of in utero transplantation. LÄS MER

4. 8. Sex differences in immune response and sex hormone receptor expression in healthy individuals and during viral infection

   Författare :Peik M. A. Brundin; Anders F. Johansson; Ivan Nalvarte; Carl-Johan Treutiger; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; immune response; menstrual cycle; puumala virus; hantavirus; torque teno virus; sex hormones; sex hormone receptors; estrogen receptors; estrogen receptor beta2; sex differences; microbiome; virome; endocrinology; peripheral blood mononuclear cells; qPCR; Infectious Diseases; infektionssjukdomar; medicinsk virologi; Medical Virology; immunologi; Immunology; Medical Cell Biology; medicinsk cellbiologi; molekylärbiologi; Molecular Biology; Medicine; medicin; obstetrik och gynekologi; Obstetrics and Gynaecology;

   Sammanfattning : There is sex-bias in morbidity and mortality from infectious diseases. Infections kill more men than women and several studies have pointed out differences in the immune system as a reason. The sex hormones estrogen, progesterone and testosterone all shape the effect of the immune response on multiple levels. LÄS MER

5. 9. Biological importance of cytomegalovirus infection in health and disease : profound effects of infection on monocyte and smooth muscle cell function

   Författare :Sara Gredmark; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Cytomegalovirus; monocyte macrophage; dendritic cell; cellular differentiation; latency; atherosclerosis; smooth muscle cells;

   Sammanfattning : Human cytomegalovirus (HCMV) is a herpesvirus. Following a primary infection, HCMV persists in the body in a latent form and most adults are virus carriers. Infection and reactivation of HCMV occur in inummocompromised patients causing severe disease and appear to be the result of inflammatory processes. LÄS MER

7. 10. Innate and adaptive cellular immunity in chronic HCV and HIV-1 infection

   Författare :Veronica D Gonzalez; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :HCV; HIV-1; co-infection; adaptive immunity; innate immunity; NK cell; NKT cell; CD4 T cell; CD8 T cell; IFNalpha; ribavirin; immune activation;

   Sammanfattning : Viral infections are initially countered by an innate immune response as a first line of defence followed by an adaptive immune response. However, certain viruses successfully evade cellular immune responses and establish chronic infection. LÄS MER