Sökning: "Breast cancer risk"

Visar resultat 16 - 20 av 351 avhandlingar innehållade orden Breast cancer risk.

  1. 16. Wnt-5a Signalling in Human Mammary Cells: Implications for the Development of Breast Cancer

    Författare :Marzieh Jönsson; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oncology; Cytology; signalling; breast cancer; Wnt-5a; mammary epithelial cells; cancer; onkologi; Cytologi; cancerology;

    Sammanfattning : The Wnt-5a gene encodes a secreted protein that regulates several normal processes in embryonic and adult tissues by as yet unknown mechanisms. Expression of Wnt-5a protein does not cause cell transformation, but it instead counteracts the effects induced by transforming Wnts. LÄS MER

  3. 17. Characterization of Male Breast Cancer : From Molecule to Clinical Outcome

    Författare :Cecilia Nilsson; Marie-Louise Fjällskog; Leif Bergkvist; Thomas Hatschek; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; male breast cancer; immunohistochemistry; prognostic; cyclins; gene expression; genomic profiling; Oncology; Onkologi; Oncology; Onkologi;

    Sammanfattning : The aim of this thesis was to investigate different aspects of male breast cancer (MBC), and to compare these with findings in female breast cancer (FBC). In paper I, a population–based study was performed to investigate possible differences in treatment and outcome between MBC and FBC patients. LÄS MER

  4. 18. Impact of Lifestyle, Hormones, and Genes on Breast Cancer

    Författare :Maria Hietala; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; BRCA1; BRCA2; androgen receptor; CAG; GGC; polymorphism; htSNP; oral contraceptives; testosterone; breast-feeding; prolactin; premenopausal women; CYP2D; complementary and alternative medicin; antidepressants;

    Sammanfattning : Approximately 7000 women are diagnosed and 1500 women die from breast cancer in Sweden every year. The aim of this thesis was to study the interplay of polymorphisms, hormone levels, lifestyle, and the use of concomitant medication in relation to risk and prognosis in two cohorts: one composed of young healthy women from high-risk breast cancer families and the other of breast cancer patients from the general population. LÄS MER

  5. 19. Selenium and Breast Cancer. Is It Protective? Epidemiologic Evidence Regarding Risk and Prognosis

    Författare :Malte Sandsveden; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast neoplasms; Selenium; Epidemiology; cancer biomarkers; Single nucleotide polymophisms; Thyroid hormone receptor alpha; Dietary selenium intake; Serum selenium; Genetic Risk;

    Sammanfattning : .... LÄS MER

  7. 20. Breast cancer in young women. Aspects of heredity and contralateral disease

    Författare :Annelie Augustinsson; LUCC: Lunds universitets cancercentrum; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; Early-onset; Genetic counseling; Genetic testing; BRCA1 and BRCA2; Contralateral breast cancer; Breast cancer; Early-onset; Genetic counseling; Genetic testing; BRCA1 and BRCA2; Contralateral breast cancer;

    Sammanfattning : Breast cancer is the most commonly diagnosed cancer among women in Sweden, as well as worldwide. In Sweden, 8,288 women were diagnosed with invasive breast cancer in 2019, out of whom approximately 1.5% were younger than 35 years of age. LÄS MER