Sökning: "Bordetella pertussis"

Visar resultat 11 - 14 av 14 avhandlingar innehållade orden Bordetella pertussis.

  1. 11. Bacterial toxins for cancer treatment

    Författare :David Johansson; Parviz Behnam-Motlagh; Kjell Grankvist; Anders Johansson; Roger Henriksson; Bo Baldetorp; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alpha‐toxin; AC‐toxin; mesothelioma; lung cancer; glioma; breast cancer; caspases; MAP-Kinase; verotoxin‐1; cisplatin; apoptosis; Gb3; drug resistance; Clinical chemistry; Klinisk kemi;

    Sammanfattning : Even though anti‐cancer chemotherapy has been continuously improved during the last decades. problems with adverse effects and drug resistance still constitutes a considerable obstacle and sets a demand for new effective treatment options. LÄS MER

  3. 12. Human polymorphonuclear granulocytes in inflammation : studies with an emphasis on nitric oxide

    Författare :Gerd Lärfars; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Polymorphonuclear granulocytes; inflammation; nitric oxide; leukotrienes; tumor necrois factor; rheumatoid arthritis; interferon-gamma; chronic granulomatous disease;

    Sammanfattning : The function of the polymorphonuclear neutrophil granulocyte (PMN) is of vital importance in inflammation. For the defense against infections PMNs are armored with different weapons such as chemotaxis, phagocytosis and production of cytotoxic substances. LÄS MER

  4. 13. Antigen presentation by dendritic cells and immunomodulation by cholera toxin B subunit. Implications for vaccine development

    Författare :Annie George-Chandy; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dendritic cells; cholera toxin B subunit; antigen-presentation;

    Sammanfattning : Antigen presentation by dendritic cells is the first event that takes place upon initiation of an acquired immune response. The inductive events during antigen presentation will essentially govern the orientation and the magnitude of the subsequent immune responses. LÄS MER

  5. 14. Human truncated thioredoxin (Trx80) as a novel mitogenic cytokine for white blood cells

    Författare :Klas Pekkari; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Thioredoxin (Trx) is a 12 kDa protein present in all species with a well-conserved active site sequence comprising -Cys-Gly-Pro-Cys-, which catalyzes oxido-reductase reactions. Trx regulates the activity of transcription factors and intracellular signalling pathways, and secreted Trx is a co-cytokine with several interleukins. LÄS MER