Sökning: "Avdelningen För Molekylärmedicin Och Genterapi"

Visar resultat 11 - 15 av 48 avhandlingar innehållade orden Avdelningen För Molekylärmedicin Och Genterapi.

  1. 11. Novel Insights into Haematopoietic Stem Cell Regulation and Function

    Författare :Sarah Warsi; Avdelningen för molekylärmedicin och genterapi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Haematopoiesis; Haematopoietic stem cell; Stem cell regulation; Haematopoietic stem cell transplantation;

    Sammanfattning : The haematopoietic stem cell (HSC) is a somatic stem cell essential for life long haematopoiesis; HSCs have the capability to differentiate into all mature types of blood cells and can also undergo self-renewal to maintain their own numbers. They also have the potential to reconstitute a complete haematopoietic system following HSC transplantation, also known as bone marrow transplantation, which is used to treat many haematopoietic disorders. LÄS MER

  3. 12. The Human Lung Epithelium in Health and Disease

    Författare :Sofia Wijk; Avdelningen för molekylärmedicin och genterapi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Basal cells; Regeneration; Human; Single-cell; scRNA-seq; COPD; IPF; Stem Cell Therapy;

    Sammanfattning : .... LÄS MER

  4. 13. Unravelling mechanisms of hematopoietic stem cell expansion

    Författare :Kristijonas Zemaitis; Avdelningen för molekylärmedicin och genterapi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematopoietic stem cell; UM171; RNAi RNA-interference ; Targeted protein degradation;

    Sammanfattning : .... LÄS MER

  5. 14. Protein kinase C epsilon and neurite outgrowth

    Författare :Ruth Zeidman; Avdelningen för molekylärmedicin och genterapi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine human and vertebrates ; Medicin människa och djur ;

    Sammanfattning : Protein kinase C (PKC) is a serine/threonine kinase family with 10 identified isoforms. The contribution of PKC isoforms to cell growth and differentiation, with focus on neurite outgrowth, was investigated, using neuroblastoma and immortalised neural cells as model systems. LÄS MER

  7. 15. bHLH transcription factors in differentiating neuroblastoma cells

    Författare :Anna Grynfeld; Avdelningen för molekylärmedicin och genterapi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bHLH; Neuroblastoma; HES-1; HASH-1; N-Myc; differentiation; Mad; Medicine human and vertebrates ; Medicin människa och djur ;

    Sammanfattning : Neuroblastoma is a tumor of the sympathetic nervous system, and arises during early childhood. The tumor is highly heterogeneous and evidence, such as expression of genes normally only expressed during embryonic and fetal stages, suggests that the tumor is of embryonic origin and that the tumor arises as a consequence of perturbed differentiation during the development of the sympathetic nervous system. LÄS MER