Sökning: "Arene"

Visar resultat 6 - 10 av 17 avhandlingar innehållade ordet Arene.

  1. 6. Asymmetric Transfer Hydrogenation of Aromatic Ketones : Catalyst Development and Mechanistic Studies

    Författare :Sofia Nordin; Torbjörn Frejd; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; transfer hydrogenation; aza-norbornyl structure; amino acid derivatives; amino alcohols; ruthenium; concerted mechanism; asymmetric catalysis.; Organisk kemi; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

    Sammanfattning : This thesis describes the development and evaluation of new chiral Ru(arene)(amino alcohol) catalysts for the transfer hydrogenation of aromatic ketones using isopropanol as the hydrogen source. Two mechanistic studies of the Ru(arene)(amino alcohol) catalyzed transfer hydrogenation of acetophenone were also conducted. The Ru(arene)[(1S,3R,4R)-3. LÄS MER

  3. 7. A Microcalorimetric Study of Macrocyclic Complexes in Aqueous Solution

    Författare :Magnus Stödeman; Fysikalisk kemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemistry; Aqueous Solution; Calixarene; Cyclodextrin; Vaporization; Macrocyclic compounds; Microcalorimetry; Kemi;

    Sammanfattning : The present work involves a microcalorimetric characterization of the interactions among macrocyclic compounds and aliphatic molecules in aqueous solution. The macrocyclic compounds used in the study are a-,b- and g-cyclodextrin and 25,26,27,28-tetrahydroxycalix[4]arene-5,11,17,23- tetrasulphonate. LÄS MER

  4. 8. Redefining the essential molecular aspects that drive interactions between small molecules and G-quadruplex DNA

    Författare :Måns Andréasson; Erik Chorell; Anna Linusson Jonsson; Jan Kihlberg; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; G-Quadruplexes; DNA; Oncogenes; G4 ligands; heterocycles; macrocycles; organic synthesis; molecular interactions; rational compound design; medicinal chemistry.; medicinal chemistry; läkemedelskemi; organisk kemi; Organic Chemistry;

    Sammanfattning : G-Quadruplex (G4) structures are secondary nucleic acid structures located in guanine-rich regions of DNA and RNA sequences, involved in gene regulation and cellular maintenance. Efforts to target G4s in a therapeutic setting are scarce, mainly due to vague details about the binding interactions between the ligands and the G4 structure combined with the lack of emphasis on drug-like properties early in the ligand development process. LÄS MER

  5. 9. Synthesis, Characterization and Application of Multiscale Porous Materials

    Författare :Linda Hussami; Lars Kloo; Mika Linden; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Inorganic chemistry; Oorganisk kemi;

    Sammanfattning : This thesis work brings fresh insights and improved understanding of nanoscale materials through introducing new hybrid composites, 2D hexagonal in MCM-41 and 3D random interconnected structures of different materials, and application relevance for developing fields of science, such as fuel cells and solar cells.New types of porous materials and organometallic crystals have been prepared and characterized in detail. LÄS MER

  7. 10. Asymmetric transfer hydrogenation of aromatic ketones and azirines with NH-ligands

    Författare :Peter Roth; Krister Zetterberg; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Organisk kemi; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

    Sammanfattning : The Ru(arene)[(1S, 3R, 4R)-3-(Hydroxymethyl)-2-azabicyclo[2.2.1]heptane catalyst was optimized as ligand in the asymmetric transfer hydrogenation of ketones and resulted in increased activity and enantioselectivity of the catalyst. LÄS MER