Sökning: "Antigen presentation"

Visar resultat 6 - 10 av 160 avhandlingar innehållade orden Antigen presentation.

  1. 6. Dendritic cell interactions with Gram negative bacteria

    Författare :Mattias Svensson; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mycology; virology; Major histocompatibility complex molecules; Dendritic cells; Gram negative bacteria; Antigen processing; Antigen presentation; bacteriology; Microbiology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Sammanfattning : The interaction between murine bone marrow-derived dendritic cells (DC) and the Gram negative bacteria Salmonella typhimurium and Escherichia coli have been characterised. These studies showed that DC phagocytosed and processed S. typhimurium and E. LÄS MER

  3. 7. Feedback Enhancement of Immune Responses by IgE, IgM, and IgG3 Antibodies

    Författare :Zhoujie Ding; Birgitta Heyman; Eva Severinson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IgE; IgM; IgG3; antibody responses; T-cell responses; antigen transportation; antigen presentation; complement; complement receptors 1 and 2; Immunologi; Immunology;

    Sammanfattning : Antibodies can enhance or suppress the immune responses against their specific antigens. This phenomenon is known as antibody-mediated feedback regulation. We have studied the mechanisms underlying IgE-, IgM-, and IgG3-mediated enhancement of immune responses in mouse models using intravenous immunization. LÄS MER

  4. 8. Characterization of antigen-presenting cell function in vitro and ex vivo

    Författare :Pablo Giusti; Marita Troye-Blomberg; Stefania Varani; David Roberts; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Antigen presentation; Dendritic Cells; Macrophages; Toll-like receptors; Malaria; Microbiology; immunology; infectious diseases; Mikrobiologi; immunologi; infektionssjukdomar; immunologi; Immunology;

    Sammanfattning : Long-term protective immunity depends on proper initiation of professional antigen-presenting cells (APCs). Autoimmune disorders and certain infections can cause disease through modulation of APCs and thereby affecting the outcome of these diseases. LÄS MER

  5. 9. Presentation of Salmonella antigens by dendritic cells

    Författare :Ulf Yrlid; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serology; Immunology; antigen processing and presentation; Dendritic cells; Salmonella; transplantation; Immunologi; serologi;

    Sammanfattning : This study investigates the interaction between dendritic cells (DC) and the Gram negative intracellular bacterium Salmonella typhimurium. Using in vitro and in vivo approaches, the capacity of DC to directly and indirectly present antigens from Salmonella-infected cells, cytokine production by infected DC, and activation of bacteria-specific T cells was analyzed. LÄS MER

  7. 10. Processing and presentation of exogenous antigen by dendritic cells

    Författare :Liying Chen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :DC; vesicular MHC-I processing; Adenosine; CD 1 d; TACA;

    Sammanfattning : Dendritic cells (DC) play a key role in the immune system. In this thesis, we have investigated and characterized pathways for the processing and presentation of exogenous OVA on MHC-I ("cross-presentation") and how these were influenced by the purine nucleoside Adenosine (Ado), an immune regulator that accumulates to high concentrations at sites of inflammation and tumor growth. LÄS MER