Sökning: "Antigen processing"
Visar resultat 1 - 5 av 71 avhandlingar innehållade orden Antigen processing.
Sammanfattning : The interaction between murine bone marrow-derived dendritic cells (DC) and the Gram negative bacteria Salmonella typhimurium and Escherichia coli have been characterised. These studies showed that DC phagocytosed and processed S. typhimurium and E. LÄS MER
Sammanfattning : Dendritic cells (DC) play a key role in the immune system. In this thesis, we have investigated and characterized pathways for the processing and presentation of exogenous OVA on MHC-I ("cross-presentation") and how these were influenced by the purine nucleoside Adenosine (Ado), an immune regulator that accumulates to high concentrations at sites of inflammation and tumor growth. LÄS MER
3. Computational analyses of biological sequences -applications to antibody-based proteomics and gene family characterization
Sammanfattning : Following the completion of the human genome sequence, post-genomic efforts have shifted the focus towards the analysis of the encoded proteome. Several different systematic proteomics approaches have emerged, for instance, antibody-based proteomics initiatives, where antibodies are used to functionally explore the human proteome. LÄS MER
Sammanfattning : Major histocompatibility complex (MHC) class I molecules present antigenic peptides to CD8+ T cells. The peptides are generated by proteasomes in the cytosol, then translocated across the membrane of the endoplasmic reticulum (ER) by the transporter associated with antigen processing (TAP). LÄS MER
5. Antigen processing and presentation by B lymphocytes decorated with passively incorporated antibodies
Sammanfattning : .... LÄS MER