Sökning: "Antibodies IgA IgG"

Visar resultat 16 - 20 av 81 avhandlingar innehållade orden Antibodies IgA IgG.

  1. 16. Elimination of circulation IgA and IgS immune complexes : An experimental study in mice, rats and guinea pigs

    Författare :Anders Johansson; Ann Kari Lefvert; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Immune complexes were formed between dinitrophenyl- (DNP-) conjugated human serum albumin (HSA) and anti-DNP antibodies (monoclonal mouse IgA or polyclonal rabbit IgG). Blood clearance and tissue distribution of intravenously injected labelled antigen and immunecomplex preparations were studied in mice, rats and guinea pigs. LÄS MER

  2. 17. HIV-induced humoral immune response with specific relevance to IgA

    Författare :Pia Skott; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HIV; secretory lgA; neutralizing antibodies; mucosal immunity;

    Sammanfattning : Human Immunodeficiency Virus (HIV) transmission occurs primarily after hetero- and homosexual contact and across mucosal surfaces. The immune response in mucosal tissues is typified by secretory immunoglobulin A (SIgA), which is the predominant lg class in human external secretions. LÄS MER

  3. 18. The genetics of IgA deficiency : a ‛two-disease’ approach

    Författare :Ning Wang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Selective IgA deficiency (IgAD) is the most common primary immunodeficiency disorder in Caucasians with a prevalence of approximately 1:600 in the general population. It is defined as serum IgA levels below or equal to 0.07 g/l with normal serum levels of IgM and IgG above the age of 4. LÄS MER

  4. 19. Circulating and Mucosal Antibodies to Citrullinated Antigens in Rheumatoid Arthritis

    Författare :Anna Svärd; Thomas Skogh; Alf Kastbom; Carl Turesson; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint inflammation and subsequent destruction of cartilage and bone. The etiology is largely unknown, although genetic as well as environmental factors are involved. The manifestations and consequences of RA differ between individuals. LÄS MER

  5. 20. Deciphering Binding Patterns of Therapeutic Antibodies with Immune Cells : From Method Development to Application

    Författare :Sina Bondza; Jos Buijs; Marika Nestor; Mark Cragg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; affinity; binding kinetics; CD20; cell-based assay; immunology; receptor-ligand interaction; therapeutic antibody; Immunologi; Immunology; Medical Cell Biology; Medicinsk cellbiologi;

    Sammanfattning : Reversible binding, for example between signaling molecules and receptors on the cell surface, is one of the main means to communicate information in cellular systems. Knowledge about how molecules interact is crucial for both understanding biological function and for therapeutic intervention. LÄS MER