Sökning: "Amphiregulin"
Visar resultat 1 - 5 av 6 avhandlingar innehållade ordet Amphiregulin.
1. Host-bacteria interactions : Host cell responses and bacterial pathogenesis
Sammanfattning : Helicobacter pylori colonizes the human stomach, where it causes gastritis that may develop into peptic ulcer disease or cancer when left untreated. Neisseria gonorrhoeae colonizes the urogenital tract and causes the sexually transmitted disease gonorrhea. LÄS MER
2. Gene expression in the dorsal root ganglion and the role of PAI-1 and amphiregulin during regeneration
Sammanfattning : This thesis is concerned with two aspects of peripheral nerve injury. First the early changes in the gene expression of the dorsal root ganglion (DRG) in response to sciatic nerve injury as revealed by micro-array analysis. Second an examination of the effect of PAI-1 and amphiregulin on survival and axonal outgrowth from DRG. LÄS MER
3. Stem cells : proliferation, differentiation, migration
Sammanfattning : A stem cell is demanding and requires precise conditions to carry out its unique tasks. This includes proliferation as an undifferentiated stem cell, differentiation to more mature cell types, migration through tissue to its final destination, and functional integration into the cellular network. LÄS MER
4. Identification of Tumor Cell- and Stroma Derived Biomarkers of Treatment Response in Head and Neck Cancer
Sammanfattning : Head and neck squamous cell carcinoma (HNSCC) poses a major health problem in the world with approximately 600 000 new cases yearly. Treatment resistance is a major problem within this patient group and despite advances in treatment strategies the overall survival rate has unfortunately not increased. LÄS MER
5. Matrix metalloproteases and cell motility in malignant mesothelioma
Sammanfattning : Invasion and metastasis of malignant tumor cells requires destruction of and migration through extracellular matrix (ECM) such as basement membrane and interstitial stroma. The ECM-degrading proteases produced by tumor cells and stromal cells and cell motility play a crucial role in this process. LÄS MER